Detalhe da pesquisa
1.
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.
Biochem Biophys Res Commun
; 457(4): 669-75, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25615820
2.
Cell proliferation arrest and redox state status as part of different stages during senescence establishment in mouse fibroblasts.
Biogerontology
; 15(2): 165-76, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24347027
3.
The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background.
Aging (Albany NY)
; 16(7): 5829-5855, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38613792
4.
Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice.
Geroscience
; 45(3): 1451-1469, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976489
5.
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy.
Nat Commun
; 14(1): 2367, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37185259
6.
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
Proc Natl Acad Sci U S A
; 106(9): 3059-64, 2009 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19223593
7.
Brain cellular senescence in mouse models of Alzheimer's disease.
Geroscience
; 44(2): 1157-1168, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35249206
8.
Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis.
Cancers (Basel)
; 14(12)2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35740528
9.
Genetic diversity estimates for the Caenorhabditis Intervention Testing Program screening panel.
MicroPubl Biol
; 20222022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35098051
10.
Rapamycin impairs bone accrual in young adult mice independent of Nrf2.
Exp Gerontol
; 154: 111516, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389472
11.
Is the oxidative stress theory of aging dead?
Biochim Biophys Acta
; 1790(10): 1005-14, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19524016
12.
Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span.
FASEB J
; 23(10): 3601-8, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19487311
13.
Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells from Long-Lived Species.
J Gerontol A Biol Sci Med Sci
; 75(8): 1439-1447, 2020 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32515471
14.
The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis.
Oncogene
; 39(18): 3693-3709, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152405
15.
The in vivo gene expression signature of oxidative stress.
Physiol Genomics
; 34(1): 112-26, 2008 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18445702
16.
Proteasome modulates mitochondrial function during cellular senescence.
Free Radic Biol Med
; 44(3): 403-14, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17976388
17.
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress.
Free Radic Biol Med
; 44(5): 882-92, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18164269
18.
Diminished acute phase response and increased hepatic inflammation of aged rats in response to intraperitoneal injection of lipopolysaccharide.
J Gerontol A Biol Sci Med Sci
; 63(12): 1299-306, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19126842
19.
Rapamycin and the inhibition of the secretory phenotype.
Exp Gerontol
; 94: 89-92, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28167236
20.
[Cellular senescence as a common denominator in age-related diseases]. / La senescencia celular como denominador común de enfermedades asociadas a la edad.
Rev Med Inst Mex Seguro Soc
; 55(4): 490-497, 2017.
Artigo
em Espanhol
| MEDLINE | ID: mdl-28591504