Detalhe da pesquisa
1.
Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma.
Gastroenterology
; 166(5): 886-901.e7, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096955
2.
Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinoma.
Hepatology
; 79(4): 941-958, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37018128
3.
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Hepatology
; 78(3): 709-726, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999529
4.
Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma.
J Hepatol
; 79(1): 93-108, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868481
5.
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids.
Hepatology
; 76(6): 1617-1633, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35030285
6.
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
J Hepatol
; 77(4): 991-1004, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750136
7.
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models.
J Hepatol
; 77(1): 177-190, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217064
8.
Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease.
Hepatology
; 73(1): 186-203, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32145077
9.
Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models.
J Hepatol
; 74(2): 394-406, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32950589
10.
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.
J Hepatol
; 75(2): 363-376, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887357
11.
Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets.
Liver Int
; 40(7): 1670-1685, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32378324
12.
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
Gut
; 68(3): 533-546, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29374630
13.
MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma.
Hepatology
; 68(2): 561-573, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29406621
14.
MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation.
Hepatology
; 67(4): 1420-1440, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28922472
15.
The tumour microenvironment and immune milieu of cholangiocarcinoma.
Liver Int
; 39 Suppl 1: 63-78, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30907492
16.
Primary biliary cholangitis: A tale of epigenetically-induced secretory failure?
J Hepatol
; 69(6): 1371-1383, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193962
17.
The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma.
Biochim Biophys Acta Mol Basis Dis
; 1864(4 Pt B): 1468-1477, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28782657
18.
Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.
Hepatology
; 66(4): 1125-1143, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28555885
19.
TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury.
J Immunol
; 196(10): 4298-310, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27053764
20.
SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma.
J Hepatol
; 67(1): 72-83, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28237397