Detalhe da pesquisa
1.
Human metabolic individuality in biomedical and pharmaceutical research.
Nature
; 477(7362): 54-60, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21886157
2.
Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits.
Hum Mol Genet
; 23(2): 534-45, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24014485
3.
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.
PLoS Genet
; 8(7): e1002805, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22829776
4.
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PLoS Genet
; 8(5): e1002741, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22693455
5.
Genetic associations with lipoprotein subfractions provide information on their biological nature.
Hum Mol Genet
; 21(6): 1433-43, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22156577
6.
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
PLoS Genet
; 7(10): e1002333, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22028671
7.
Genetic determinants of serum testosterone concentrations in men.
PLoS Genet
; 7(10): e1002313, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21998597
8.
A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3.
Hum Mol Genet
; 20(6): 1241-51, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21216879
9.
On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies.
BMC Bioinformatics
; 13: 120, 2012 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22672667
10.
Common genetic variants associate with serum phosphorus concentration.
J Am Soc Nephrol
; 21(7): 1223-32, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20558539
11.
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Nat Genet
; 48(10): 1171-1184, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618452
12.
Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes.
Circ Cardiovasc Genet
; 8(1): 131-40, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25477429
13.
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.
Nat Commun
; 6: 7208, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068415
14.
Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion.
Hypertension
; 63(5): 1102-9, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591336
15.
Associations between thyroid hormones and serum metabolite profiles in an euthyroid population.
Metabolomics
; 10(1): 152-164, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24955082
16.
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids.
Genome Med
; 6(3): 25, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24678845
17.
An atlas of genetic influences on human blood metabolites.
Nat Genet
; 46(6): 543-550, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816252
18.
Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma.
Genome Med
; 5(2): 13, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23414815
19.
Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach.
Diabetes
; 62(12): 4270-6, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23884885
20.
Metabolomic markers reveal novel pathways of ageing and early development in human populations.
Int J Epidemiol
; 42(4): 1111-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23838602