Detalhe da pesquisa
1.
Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma.
Blood
; 139(10): 1541-1556, 2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818414
2.
Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma.
Proc Natl Acad Sci U S A
; 117(46): 28980-28991, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139544
3.
IL-2 receptors preassemble and signal in the ER/Golgi causing resistance to antiproliferative anti-IL-2Rα therapies.
Proc Natl Acad Sci U S A
; 116(42): 21120-21130, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570576
4.
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.
Mol Cancer
; 20(1): 86, 2021 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34092254
5.
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Proc Natl Acad Sci U S A
; 114(15): 3975-3980, 2017 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356514
6.
Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma.
Proc Natl Acad Sci U S A
; 113(6): 1624-9, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26811457
7.
Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.
Proc Natl Acad Sci U S A
; 112(40): 12480-5, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396258
8.
Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.
Am J Hematol
; 92(9): 892-901, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28543380
9.
Phase 1 trial of IL-15 trans presentation blockade using humanized Mikß1 mAb in patients with T-cell large granular lymphocytic leukemia.
Blood
; 121(3): 476-84, 2013 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23212516
10.
Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15Rα.
Blood
; 117(15): 4032-40, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21304101
11.
Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma.
Blood Adv
; 6(7): 2346-2360, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35030628
12.
A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma.
Leukemia
; 35(7): 1976-1989, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184494
13.
Enhanced efficacy of JAK1 inhibitor with mTORC1/C2 targeting in smoldering/chronic adult T cell leukemia.
Transl Oncol
; 14(1): 100913, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33129109
14.
Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies.
J Immunother Cancer
; 9(4)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883258
15.
Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma.
Cancer Cell
; 34(2): 286-297.e10, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057145
16.
A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-ß factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.
J Innate Immun
; 6(3): 377-93, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24577058