Detalhe da pesquisa
1.
A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators.
J Biol Chem
; 298(12): 102705, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36400200
2.
Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "Irreversibility Rule" for Protein Autoprocessing Inhibition.
Biochemistry
; 61(11): 1022-1028, 2022 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34941260
3.
Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis.
Biochemistry
; 59(6): 736-741, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32013401
4.
Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules.
Methods Enzymol
; 685: 1-41, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37245899
5.
Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism.
Chem Commun (Camb)
; 55(12): 1829-1832, 2019 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30672911