Detalhe da pesquisa
1.
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency.
Proc Natl Acad Sci U S A
; 109(21): 8253-8, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566612
2.
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma.
JCI Insight
; 5(17)2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32780726
3.
PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.
Cancer Discov
; 9(2): 220-229, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442709
4.
ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.
Cancer Discov
; 9(3): 396-415, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563872
5.
Strong regional heterogeneity in base composition evolution on the Drosophila X chromosome.
Genetics
; 174(1): 349-62, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16547109
6.
Molecular evolution in the Drosophila melanogaster species subgroup: frequent parameter fluctuations on the timescale of molecular divergence.
Genetics
; 172(3): 1711-26, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16387879
7.
ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.
Autophagy
; 13(12): 2056-2071, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28981387
8.
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma.
JCI Insight
; 7(20)2022 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36278493
9.
A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.
Cancer Discov
; 7(11): 1266-1283, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28899863
10.
Targeting the lysosome in cancer.
Ann N Y Acad Sci
; 1371(1): 45-54, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26599426
11.
Identification of secreted proteins that reflect autophagy dynamics within tumor cells.
Autophagy
; 11(1): 60-74, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25484078
12.
Multiple Gastrointestinal Polyps in Patients Treated with BRAF Inhibitors.
Clin Cancer Res
; 21(23): 5215-21, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26202952
13.
Effects of angiotensin II on vascular endothelial cells: formation of receptor-mediated reactive nitrogen species.
Biochem Pharmacol
; 65(7): 1189-97, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12663054
14.
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.
J Clin Invest
; 124(3): 1406-17, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569374
15.
Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.
Autophagy
; 10(8): 1380-90, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24991834
16.
Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma.
Autophagy
; 10(8): 1369-79, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24991839
17.
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme.
Autophagy
; 10(8): 1359-68, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24991840
18.
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma.
Clin Cancer Res
; 17(10): 3478-89, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325076
19.
A simplified method for identification of human cardiac myosin heavy-chain isoforms.
Biotechnol Appl Biochem
; 37(Pt 1): 27-30, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12578548