Detalhe da pesquisa
1.
Differentiation is accompanied by a progressive loss in transcriptional memory.
BMC Biol
; 22(1): 58, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38468285
2.
Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain.
EMBO J
; 39(21): e99520, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32935369
3.
LC-MS/MS Bioanalysis of Radioligand Therapeutic Drug Candidate for Preclinical Toxicokinetic Assessment.
Anal Chem
; 95(28): 10812-10819, 2023 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402311
4.
scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data.
In Silico Biol
; 15(1-2): 11-21, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37927254
5.
Toxicokinetics in preclinical drug development of small-molecule new chemical entities.
Biomed Chromatogr
; 37(7): e5553, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36415962
6.
Evidence for close molecular proximity between reverting and undifferentiated cells.
BMC Biol
; 20(1): 155, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794592
7.
A derived ZW chromosome system in Amborella trichopoda, representing the sister lineage to all other extant flowering plants.
New Phytol
; 233(4): 1636-1642, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34342006
8.
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints.
Nucleic Acids Res
; 47(10): 5114-5125, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30916335
9.
Probabilistic count matrix factorization for single cell expression data analysis.
Bioinformatics
; 35(20): 4011-4019, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865271
10.
Development and validation of an LC-MS/MS method for the quantitative analysis of the adenosine A2a receptor antagonist NIR178 and its monohydroxy metabolite in human plasma: Application to clinical pharmacokinetics.
Biomed Chromatogr
; 34(10): e4909, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32485782
11.
High dimensional classification with combined adaptive sparse PLS and logistic regression.
Bioinformatics
; 34(3): 485-493, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28968879
12.
SNP calling from RNA-seq data without a reference genome: identification, quantification, differential analysis and impact on the protein sequence.
Nucleic Acids Res
; 44(19): e148, 2016 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27458203
13.
The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells.
PLoS Genet
; 10(5): e1004282, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24785686
14.
Modeling overdispersion heterogeneity in differential expression analysis using mixtures.
Biometrics
; 72(3): 804-14, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26683201
15.
Effect of esomeprazole, a proton pump inhibitor on the pharmacokinetics of sonidegib in healthy volunteers.
Br J Clin Pharmacol
; 82(4): 1022-9, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27277189
16.
Analysis of small molecule antibody-drug conjugate catabolites in rat liver and tumor tissue by liquid extraction surface analysis micro-capillary liquid chromatography/tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 30(7): 823-32, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969923
17.
The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry.
Anal Bioanal Chem
; 408(6): 1687-99, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26758601
18.
New microfluidic-based sampling procedure for overcoming the hematocrit problem associated with dried blood spot analysis.
Anal Chem
; 87(4): 2068-71, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25607538
19.
Pharmacokinetics of fingolimod and metabolites in subjects with severe renal impairment: An open-label, single-dose, parallel-group study.
Int J Clin Pharmacol Ther
; 53(10): 847-54, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308173
20.
Application of a deuterium replacement strategy to modulate the pharmacokinetics of 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethylpyrazolo[5,1-b]oxazole, a novel CRF1 antagonist.
Drug Metab Dispos
; 42(5): 954-62, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24616265