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1.
Acta Neurochir Suppl ; 127: 201-205, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31407086

RESUMO

Transcranial Doppler ultrasonography (TCD) is a noninvasive technique used to detect vasospasms following a subarachnoid hemorrhage. While the gold standard to evaluate vasospasms is angiography, this technique is invasive and poses additional risks as compared to TCD. TCD is performed by insonating circle of Willis arteries to measure cerebral flow velocity. TCD allows dynamic monitoring of CBF-V and vessel pulsatility, with a high temporal resolution. It is relatively inexpensive, repeatable, and portable; however, the performance of TCD is highly operator dependent and can be difficult, especially with inadequate acoustic windows. This review summarizes the use of transcranial Doppler ultrasonography (TCD) for the assessment of cerebral vasospasm.


Assuntos
Hemorragia Subaracnóidea , Vasoespasmo Intracraniano , Humanos , Hemorragia Subaracnóidea/diagnóstico por imagem , Ultrassonografia Doppler Transcraniana , Vasoespasmo Intracraniano/diagnóstico por imagem
2.
J Med Case Rep ; 18(1): 485, 2024 Oct 08.
Artigo em Inglês | MEDLINE | ID: mdl-39375744

RESUMO

BACKGROUND: Vertebral artery compression syndrome is a rare condition defined as the clinical presentation of dizziness, vertigo, ataxia, dysarthria, dysphagia, progressive or acute paralysis, hemisensory loss, and cervical myelopathy secondary to compression of the medulla and upper spinal cord by the vertebral artery. CASE DESCRIPTION: Here we describe a 57-year-old Mexican-American male with bulbar symptoms, positional vertigo, and diplopia. The patient's symptoms were managed through microsurgical decompression of the medulla utilizing a far lateral transcondylar approach. The patient reported clinical improvement on follow-up. CONCLUSION: This case underscores the clinical complexity and heterogeneity of this rare neurovascular pathology and the importance of elucidating the pathophysiological mechanisms underlying the symptomatic presentation of vertebral artery compression syndrome.


Assuntos
Bulbo , Cirurgia de Descompressão Microvascular , Artéria Vertebral , Humanos , Masculino , Pessoa de Meia-Idade , Cirurgia de Descompressão Microvascular/métodos , Artéria Vertebral/diagnóstico por imagem , Artéria Vertebral/cirurgia , Insuficiência Vertebrobasilar/cirurgia , Insuficiência Vertebrobasilar/complicações , Insuficiência Vertebrobasilar/diagnóstico por imagem , Resultado do Tratamento , Vertigem/etiologia , Compressão da Medula Espinal/cirurgia , Compressão da Medula Espinal/etiologia , Compressão da Medula Espinal/diagnóstico por imagem , Diplopia/etiologia , Diplopia/cirurgia , Imageamento por Ressonância Magnética
3.
Clin Anat ; 26(4): 436-43, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-22576639

RESUMO

The aim of this study was to investigate the relationships/variations between the facial nerve hiatus (FNH) and middle cranial fossa neuro-vascular structures. Twenty CT-scanned middle cranial fossae of fresh adult cadavers were used; the greater superficial petrosal nerves, and critical neuro-vascular structures were identified. Using the FNH as a reference point, a neuronavigation system was used to measure the distance between each structure and the FNH. The coefficient of variation (CV) was used to quantify the degree of variation among each distance. The mean distances and standard deviations between the various landmarks and the FNH, and the associated CV were analyzed. Furthermore, a microanatomical map of the structures hidden in the middle fossa based on the greater superficial petrosal nerve was generated. The most reliable relationships of the FNH were with the internal auditory canal (CV = 14.59), and with the vertical portion of the intrapetrous internal carotid artery (CV = 15.54). Our data demonstrate that the FNH can be used as anatomical landmark to plot the position of several hidden neurovascular structures when performing a middle-fossa skull base approach. However, the pattern and the variation of these structures had to be recognized.


Assuntos
Fossa Craniana Média/anatomia & histologia , Fossa Craniana Média/diagnóstico por imagem , Nervo Facial/anatomia & histologia , Nervo Facial/diagnóstico por imagem , Adulto , Cadáver , Artéria Carótida Interna/anatomia & histologia , Orelha Interna/anatomia & histologia , Humanos , Neuronavegação , Tomografia Computadorizada por Raios X
4.
World Neurosurg ; 175: e969-e975, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37084845

RESUMO

BACKGROUND: Patients undergoing intracranial surgery experience significant perioperative pain and are typically treated with short-acting opioids. Methadone, with its prolonged half-life and multimodal central nervous system effects, presents a promising option for managing postcraniotomy pain. Despite its proven efficacy in other types of surgeries, the use of methadone in patients undergoing craniotomy has not yet been explored. METHODS: A retrospective chart review was conducted for 60 adult patients ranging in age from 18 to 81 years who received methadone during intracranial surgeries. The primary outcome of interest was the total opioid consumption in oral morphine milligram equivalents (MMEs) and patient-reported pain scores within 24 hours and up to 72 hours postoperatively. RESULTS: The methadone dosage varied from 5 to 20 mg. In the infratentorial group, the median total MME on postoperative day 1, 2, and 3 was 30.5, 17, and 0.8, respectively, with mean pain scores of 3.56, 3.91, and 2.71. In the supratentorial group, the median total MME on postoperative day 1, 2, and 3 was 17.85, 15.4, and 1.2, with mean pain scores of 2.31, 1.68, and 2.21, respectively. Patients who were chronic opioid users had significantly higher pain scores and average opioid use (P < 0.05). None of the patients required administration of naloxone or airway interventions. Comparison with the historical control showed that our study patients had lower pain scores and MME. CONCLUSIONS: The single intraoperative dose of methadone is well tolerated by adult patients undergoing various types of intracranial surgeries, with minimal side effects, including elderly patients aged 65 years or older.


Assuntos
Analgésicos Opioides , Metadona , Adulto , Idoso , Humanos , Metadona/uso terapêutico , Estudos Retrospectivos , Manejo da Dor , Dor Pós-Operatória/tratamento farmacológico
5.
Front Pharmacol ; 14: 1124263, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36843940

RESUMO

Stroke shares a significant burden of global mortality and disability. A significant decline in the quality of life is attributed to the so-called post-stroke cognitive impairment including mild to severe cognitive alterations, dementia, and functional disability. Currently, only two clinical interventions including pharmacological and mechanical thrombolysis are advised for successful revascularization of the occluded vessel. However, their therapeutic effect is limited to the acute phase of stroke onset only. This often results in the exclusion of a significant number of patients who are unable to reach within the therapeutic window. Advances in neuroimaging technologies have allowed better assessment of salvageable penumbra and occluded vessel status. Improvement in diagnostic tools and the advent of intravascular interventional devices such as stent retrievers have expanded the potential revascularization window. Clinical studies have demonstrated positive outcomes of delayed revascularization beyond the recommended therapeutic window. This review will discuss the current understanding of ischemic stroke, the latest revascularization doctrine, and evidence from clinical studies regarding effective delayed revascularization in ischemic stroke.

6.
Neurointervention ; 17(3): 195-199, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36281539

RESUMO

Fenestrated vertebrobasilar junction aneurysms are uncommon vascular lesions. Surgical intervention remains extremely challenging due to the deep location and complex anatomy with adjacent cranial nerves and perforator vessels. Endovascular approach is safer and generally accepted as the primary treatment method. Optimal angiographic projections with three-dimensional reconstructions to guide microcatheter selection remain vital to successfully treating aneurysms with challenging fenestration anatomy. This report details the endovascular methods in two cases of fenestrated vertebrobasilar junction aneurysms with different coiling techniques.

7.
Surg Neurol Int ; 12: 382, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34513149

RESUMO

BACKGROUND: Idiopathic spinal cord herniation (ISCH) is a rare, underrecognized, and often misdiagnosed entity of unclear pathogenesis that typically presents as a slowly progressive thoracic myelopathy. There are less than 200 such cases reported in the literature. ISCH diagnosis and treatment are often delayed contributing to greater fixed neurological deficits, often leading to costly, unnecessary imaging studies, and inappropriate surgery. CASE DESCRIPTION: Here, a 48-year-old female presented with trauma-induced ISCH characterized by gradually worsening lower extremity myelopathy. CONCLUSION: Idiopathic spinal cord herniation (ISCH) is rare, often underdiagnosed posttraumatic myelopathy that, when accurately diagnosed and treated, can result in good outcomes.

8.
Acta Neurochir (Wien) ; 152(3): 509-13, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19551339

RESUMO

Biologically, the site of arthrodesis provides a microenvironment replete of growth factors and active remodeling, which is propitious for bone regrowth. There is a theoretical possibility though that this microenvironment would also provide a fertile site for metastatic deposits to occur. Although spinal fusion with various types of instrumentation is commonly used to treat various disorders, development of tumors at the site of spinal arthrodesis has not been previously reported. We present the clinical, radiographic, and pathological features of a case of previously undiagnosed metastatic adenocarcinoma, occurring 1 year following anterior arthrodesis and fusion for cervical spondylotic myelopathy at the C3-C4 level. The patient's initial radiologic presentation suggested an epidural abscess with osteomyelitic destruction of C3 and C4. Our report alerts surgeons to the possibility that metastasis may occur at the site of a previous spinal arthrodesis.


Assuntos
Adenocarcinoma/secundário , Artrodese/efeitos adversos , Neoplasias Pulmonares/patologia , Fusão Vertebral/efeitos adversos , Neoplasias da Coluna Vertebral/secundário , Espondilose/cirurgia , Adenocarcinoma/cirurgia , Regeneração Óssea/fisiologia , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/patologia , Vértebras Cervicais/cirurgia , Quimiotaxia/fisiologia , Descompressão Cirúrgica , Progressão da Doença , Discotomia/efeitos adversos , Evolução Fatal , Humanos , Peptídeos e Proteínas de Sinalização Intercelular/metabolismo , Deslocamento do Disco Intervertebral/diagnóstico por imagem , Deslocamento do Disco Intervertebral/patologia , Deslocamento do Disco Intervertebral/cirurgia , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica/patologia , Metástase Neoplásica/fisiopatologia , Metástase Neoplásica/prevenção & controle , Procedimentos Neurocirúrgicos , Osteogênese/fisiologia , Radiografia , Reoperação , Compressão da Medula Espinal/diagnóstico por imagem , Compressão da Medula Espinal/patologia , Compressão da Medula Espinal/cirurgia , Fusão Vertebral/métodos , Neoplasias da Coluna Vertebral/cirurgia , Estenose Espinal/diagnóstico por imagem , Estenose Espinal/patologia , Estenose Espinal/cirurgia , Espondilose/diagnóstico por imagem , Espondilose/patologia , Resultado do Tratamento
9.
Front Oncol ; 10: 565582, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33330036

RESUMO

Although the majority of meningiomas are slow-growing and benign, atypical and anaplastic meningiomas behave aggressively with a penchant for recurrence. Standard of care includes surgical resection followed by adjuvant radiation in anaplastic and partially resected atypical meningiomas; however, the role of adjuvant radiation for incompletely resected atypical meningiomas remains debated. Despite maximum treatment, atypical, and anaplastic meningiomas have a strong proclivity for recurrence. Accumulating mutations over time, recurrent tumors behave more aggressively and often become refractory or no longer amenable to further surgical resection or radiation. Chemotherapy and other medical therapies are available as salvage treatment once standard options are exhausted; however, efficacy of these agents remains limited. This review discusses the risk factors, classification, and molecular biology of meningiomas as well as the current management strategies, novel therapeutic approaches, and future directions for managing atypical and anaplastic meningiomas.

10.
World Neurosurg ; 143: e136-e148, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32736129

RESUMO

BACKGROUND: Although the safety and feasibility of awake craniotomy are well established for epilepsy and brain tumor surgery, its application for resection of vascular lesions, including arteriovenous malformations (AVMs) and cavernomas, is still limited. Apart from the usual challenges of awake craniotomy, vascular lesions pose several additional problems. Our goal is to determine the safety and practicality of awake craniotomy in patients with cerebral vascular malformations located near the eloquent areas, using a refined anesthetic protocol. METHODS: A retrospective case series was performed on 7 patients who underwent awake craniotomy for resection of AVMs or cavernomas located in the eloquent language and motor areas. Our protocol consisted of achieving deep sedation, without a definitive airway, using a combination of propofol, dexmedetomidine, and remifentanil/fentanyl during scalp block placement and surgical exposure, then transitioning to a wakeful state during the resection. RESULTS: Six patients had intracranial AVMs, and 1 patient had a cavernoma. Six patients had complete resection; however, 1 patient underwent repeat awake craniotomy for residual AVM nidus. The patients tolerated the resection under continuous awake neurologic and neurophysiologic testing without significant perioperative complications or the need to convert to general anesthesia with a definitive airway. CONCLUSIONS: Awake craniotomy for excision of intracranial vascular malformations located near the eloquent areas, in carefully selected patients, can facilitate resection by allowing close neuromonitoring and direct functional assessment. A balanced combination of sedative and analgesic medications can provide both adequate sedation and rapid wakeup, facilitating the necessary patient interaction and tolerance of the procedure.


Assuntos
Neoplasias Encefálicas/cirurgia , Área de Broca/cirurgia , Sedação Profunda/métodos , Hemangioma Cavernoso do Sistema Nervoso Central/cirurgia , Malformações Arteriovenosas Intracranianas/cirurgia , Córtex Motor/cirurgia , Procedimentos Neurocirúrgicos/métodos , Vigília , Área de Wernicke/cirurgia , Adolescente , Adulto , Analgésicos Opioides/uso terapêutico , Anestésicos Intravenosos/uso terapêutico , Neoplasias Encefálicas/diagnóstico por imagem , Angiografia Cerebral , Angiografia por Tomografia Computadorizada , Craniotomia/métodos , Dexmedetomidina/uso terapêutico , Feminino , Fentanila/uso terapêutico , Hemangioma Cavernoso do Sistema Nervoso Central/diagnóstico por imagem , Humanos , Hipnóticos e Sedativos/uso terapêutico , Malformações Arteriovenosas Intracranianas/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Bloqueio Nervoso/métodos , Propofol/uso terapêutico , Remifentanil/uso terapêutico , Adulto Jovem
11.
J Neurosurg ; 108(3): 591-4, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18312108

RESUMO

Sarcoidosis is a multisystemic granulomatous disease characterized by noncaseating epithelioid granulomata that affects the lung in over 90% of patients and the central nervous system (CNS) in 5-9%. Neurosarcoidosis often occurs as multifocal meningeal and parenchymal lesions, and its diagnosis is particularly difficult in the absence of concomitant systemic disease. Hypothalamic-pituitary sarcoidosis occurs in fewer than 10% of patients with neurosarcoidosis and has been previously reported in association with profound endocrinological dysfunction. The authors report the case of a patient with isolated pituitary sarcoidosis who was first evaluated for visual symptoms and showed no preoperative endocrinological dysfunction or evidence of multisystemic or other CNS involvement. To the authors' knowledge, only 1 other such presentation is previously reported in the English literature. Such presentations are diagnostically and therapeutically challenging, and definitive diagnosis requires obtaining a biopsy specimen of the lesion with histological proof of noncaseating epithelioid granuloma, as well as the exclusion of other possible entities.


Assuntos
Doenças da Hipófise/diagnóstico , Sarcoidose/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Hipófise/complicações , Doenças da Hipófise/fisiopatologia , Sarcoidose/complicações , Sarcoidose/fisiopatologia
12.
Int J Crit Illn Inj Sci ; 7(1): 58-64, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28382259

RESUMO

Although traumatic pneumocephalus is not uncommon, it rarely evolves into tension pneumocephalus (TP). Characterized by the presence of increasing amounts of intracranial air and concurrent appearance or worsening neurological symptoms, TP can be devastating if not recognized and treated promptly. We present two cases of traumatic TP and a concise review of literature on this topic. Two cases of traumatic TP are presented. In addition, a literature search revealed 20 additional cases, of which 18 had sufficient information for inclusion. Literature cases were combined with the 2 reported cases and analyzed for demographics, mechanism of injury, symptoms, time to presentation (acute <72 h; delayed >72 h), diagnostic/treatment modalities, and outcomes. Twenty cases were analyzed (17 males, 3 females, median age 26, range 8-92 years). Presentation was acute in 13/20 and delayed in 7/20 patients. Injury mechanisms included motor vehicle collisions (6/20), assault/blunt trauma to the craniofacial area (5), falls (4), and motorcycle/ bicycle crashes (3). Common presentations included depressed mental status (10/20), cerebrospinal fluid rhinorrhea (9), headache (8), and loss of consciousness (6). Computed tomography (CT) was utilized in 19/20 patients. Common underlying injuries were frontal bone/sinus fracture (9/20) and ethmoid fracture (5). Intracranial hemorrhage was seen in 5/20 patients and brain contusions in 4/20 patients. Nonoperative management was utilized in 6/20 patients. Procedural approaches included craniotomy (11/20), emergency burr hole (4), endoscopy (2), and ventriculostomy (2). Most patients responded to initial treatment (19/20). One early and one delayed death were reported. Traumatic TP is rare, tends to be associated with severe craniofacial injuries, and can occur following both blunt and penetrating injury. Early recognition and high index of clinical suspicion are important. Appropriate treatment results in improvement in vast majority of cases. CT scan is the diagnostic modality of choice for TP. REPUBLISHED WITH PERMISSION FROM: Pillai P, Sharma R, MacKenzie L, Reilly EF, Beery II PR, Papadimos TJ, Stawicki SPA. Traumatic tension pneumocephalus: Two cases and comprehensive review of literature. OPUS 12 Scientist 2010;4(1):6-11.

13.
J Neurointerv Surg ; 8(e1): e2-4, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24335806

RESUMO

Small ruptured aneurysms present a unique problem to endovascular therapy. We report a case in which a patient presented with subarachnoid hemorrhage and a very small ruptured ophthalmic artery aneurysm, for which endovascular therapy was preferred secondary to severe cardiac comorbidities. Due to the aneurysm size, a small 1.5 mm coil was needed, but presented a significant risk of migration. Conventional stent assisted coiling was considered suboptimal as the small coil could have easily migrated through the strut. We present a novel technique of flow diverter assisted coil embolization in which a coil was placed within the aneurysm and a pipeline embolization device was then partially deployed, jailing the microcatheter and coil mass. Once in place, the coil was detached, securing the aneurysm, and preventing coil migration. Through the use of a flow diverter, some degree of aneurysm protection would still be expected in the event of coil migration toward the ophthalmic artery origin.


Assuntos
Aneurisma Roto/terapia , Embolização Terapêutica/instrumentação , Aneurisma Intracraniano/terapia , Artéria Oftálmica , Próteses e Implantes , Migração de Corpo Estranho/prevenção & controle , Humanos , Masculino , Pessoa de Meia-Idade , Hemorragia Subaracnóidea/terapia
14.
BMJ Case Rep ; 20132013 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-24319025

RESUMO

Small ruptured aneurysms present a unique problem to endovascular therapy. We report a case in which a patient presented with subarachnoid hemorrhage and a very small ruptured ophthalmic artery aneurysm, for which endovascular therapy was preferred secondary to severe cardiac comorbidities. Due to the aneurysm size, a small 1.5 mm coil was needed, but presented a significant risk of migration. Conventional stent assisted coiling was considered suboptimal as the small coil could have easily migrated through the strut. We present a novel technique of flow diverter assisted coil embolization in which a coil was placed within the aneurysm and a pipeline embolization device was then partially deployed, jailing the microcatheter and coil mass. Once in place, the coil was detached, securing the aneurysm, and preventing coil migration. Through the use of a flow diverter, some degree of aneurysm protection would still be expected in the event of coil migration toward the ophthalmic artery origin.


Assuntos
Aneurisma Roto/terapia , Embolização Terapêutica/métodos , Artéria Oftálmica , Adulto , Aneurisma Roto/diagnóstico por imagem , Embolização Terapêutica/instrumentação , Procedimentos Endovasculares/métodos , Migração de Corpo Estranho/prevenção & controle , Humanos , Masculino , Hemorragia Subaracnóidea/complicações , Tomografia Computadorizada por Raios X
15.
Clin Neurol Neurosurg ; 115(7): 1058-62, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23177163

RESUMO

OBJECT: Most of the approaches used to expose the petro-clival region require a certain degree of temporal bone resection with its associated approach morbidity such as potential hearing and facial nerve compromise. Endoscopes are becoming more and more popular in neurosurgical practice. To gain insight into the benefits of using endoscopy to operate on the petro-clival region, we evaluated and compared the exposure and maneuverability obtained employing the endoscope and the microscope in retrosigmoid and pre-sigmoid approaches by using quantitative analysis based on frameless stereotaxy. METHODS: We evaluated the retrosigmoid (RS), retrolabyrinthine (RL), translabyrinthine (TL), and transcochlear (TC) approaches. Each approach was performed 4 times for a total of 16 approaches. We used a navigation system for intraoperative navigation. Each approach was evaluated vis-a-vis the area of the petro-clival/brainstem region exposed and the afforded maneuverability, both using a rigid endoscope or an operating microscope. RESULTS: The TC approach exposed the largest area at the brainstem compared to all other three approaches both in microscopic and endoscopic modes and there was no significant difference between the 2 modes (P=0.42). In the RS approach use of the 30° angled endoscope increased significantly the exposure compared to the operating microscope (respectively 460±49.7 mm(2) vs 235±25 mm(2); P=0.002). On the other hand, maneuverability was significantly decreased with the endoscope compared to the microscope in all the approaches evaluated (P=0.006). CONCLUSIONS: Integration of the endoscope into conventional petrosectomy approaches could significantly reduce the amount of temporal bone drilling for adequate visualization of the petro-clival region. However maneuverability as assessed by our model was better with the microscope than with the endoscope.


Assuntos
Fossa Craniana Posterior/cirurgia , Endoscopia/métodos , Neuronavegação/métodos , Procedimentos Neurocirúrgicos/métodos , Osso Petroso/cirurgia , Técnicas Estereotáxicas/instrumentação , Encéfalo/anatomia & histologia , Encéfalo/cirurgia , Tronco Encefálico/anatomia & histologia , Tronco Encefálico/cirurgia , Cadáver , Computadores , Fossa Craniana Posterior/anatomia & histologia , Endoscópios , Endoscopia/instrumentação , Humanos , Microscopia , Neuronavegação/instrumentação , Procedimentos Neurocirúrgicos/instrumentação , Osso Petroso/anatomia & histologia , Tomografia
16.
Neurosurgery ; 67(3 Suppl Operative): ons85-90; discussion ons90, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20679944

RESUMO

BACKGROUND: Image guidance systems are widely used in neurosurgical practice. OBJECTIVE: To compare the operational accuracy of a neuronavigation system when registration was accomplished with a commercially available surface-based autoregistration system vs other fiducial-based registrations. METHODS: We evaluated the operational accuracy of different registration methods in 20 cadaveric heads. Every specimen was prepared with 10 titanium microscrews functioning as external/internal targets and as bone fiducials. Six scalp fiducials were also affixed to each specimen that was registered with bone, scalp fiducials, and the autoregistration mask. The coordinates of all the target points were measured, first manually on the screen of the navigation system and then by touching the head of the implanted screw on the specimen. The difference between the real and virtual coordinates was calculated. RESULTS: Means of the differences for external anterior targets were 1.96, 3.12, and 3.20 mm and 1.95, 3.24, and 3.19 mm for external posterior targets for the bone fiducials, adhesive fiducials, and autoregistration mask, respectively. Means of the differences for internal anterior targets were 2.60, 3.65, and 2.16 mm and 2.91, 3.83, and 2.41 mm for internal posterior targets for the bone fiducials, adhesive fiducials, and autoregistration mask, respectively. CONCLUSION: Bone fiducial registration is associated with a statistically greater operational accuracy than scalp adhesive fiducials and the autoregistration mask in reaching anterior and posterior external targets (P < .001). Registration accomplished with the autoregistration mask is associated with a statistically greater operational accuracy in reaching internal targets than adhesive fiducials registration (P < .001) or bone fiducials registration (P < .05 and P < .01 for anterior and posterior targets, respectively).


Assuntos
Cabeça/cirurgia , Neuronavegação/instrumentação , Neuronavegação/métodos , Procedimentos Neurocirúrgicos/instrumentação , Cirurgia Assistida por Computador/métodos , Cadáver , Intervalos de Confiança , Cabeça/patologia , Humanos , Lasers , Procedimentos Neurocirúrgicos/métodos , Próteses e Implantes , Reprodutibilidade dos Testes , Titânio , Tomografia Computadorizada por Raios X/métodos
17.
Neurosurgery ; 65(6 Suppl): 53-9; discussion 59, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19935002

RESUMO

OBJECTIVE: Hearing loss after removal of vestibular schwannomas with preservation of the cochlear nerve can result from labyrinthine injury of the posterior semicircular canal and/or common crus during drilling of the posterior wall of the internal auditory meatus. Indeed, there are no anatomic landmarks that intraoperatively identify the position of the posterior semicircular canal or of the common crus. We investigated the usefulness of image guidance and endoscopy for exposure of the internal auditory canal (IAC) and its fundus without labyrinthine injury during a retrosigmoid approach. METHODS: A retrosigmoid approach to the IAC was performed on 10 whole fresh cadaveric heads after acquiring high-resolution computed tomographic scans (120 kV; slice thickness, 1 mm; field of vision, 40 cm; matrix, 512 x 512) with permanent bone-implanted reference markers. Drilling of the posterior wall of the IAC was executed with image guidance. Its most lateral area was visualized using endoscopy. RESULTS: Target registration error for the procedure was 0.28 to 0.82 mm (mean, 0.46 mm; standard deviation, 0.16 mm). The measured length of the IAC along its posterior wall was 9.7 +/- 1.6 mm. The angle of drilling (angle between the direction of drill and the posterior petrous surface) was 43.3 +/- 6.0 degrees, and the length of the posterior wall of the IAC drilled without violating the integrity of the labyrinth was 7.2 +/- 0.9 mm. The surgical maneuvers in the remaining part of the IAC, including the fundus, were performed using an angled endoscope. CONCLUSION: Frameless navigation using high-resolution computed tomographic scans and bone-implanted reference markers can provide a "roadmap" to maximize safe surgical exposure of the IAC without violating the labyrinth and leaving a small segment of the lateral IAC unexposed. Further exposure and surgical manipulation of this segment, including the fundus without additional cerebellar retraction and labyrinthine injury, can be achieved using an endoscope. Use of image guidance and an endoscope can help in exposing the entire posterior aspect of the IAC including its fundus without violating the labyrinth through a retrosigmoid approach. This technique could improve hearing preservation in vestibular schwannoma surgery.


Assuntos
Fossa Craniana Posterior/cirurgia , Orelha Interna/cirurgia , Endoscopia/métodos , Neuronavegação/métodos , Osso Petroso/cirurgia , Nervo Vestibulococlear/cirurgia , Cadáver , Ângulo Cerebelopontino/anatomia & histologia , Ângulo Cerebelopontino/cirurgia , Fossa Craniana Posterior/anatomia & histologia , Cavidades Cranianas/anatomia & histologia , Cavidades Cranianas/cirurgia , Surdez/etiologia , Surdez/prevenção & controle , Orelha Interna/anatomia & histologia , Humanos , Doença Iatrogênica/prevenção & controle , Processamento de Imagem Assistida por Computador , Complicações Intraoperatórias/etiologia , Complicações Intraoperatórias/fisiopatologia , Complicações Intraoperatórias/prevenção & controle , Neuroma Acústico/cirurgia , Procedimentos Neurocirúrgicos/instrumentação , Procedimentos Neurocirúrgicos/métodos , Osso Petroso/anatomia & histologia , Cuidados Pré-Operatórios , Canais Semicirculares/anatomia & histologia , Canais Semicirculares/cirurgia , Tomografia Computadorizada por Raios X/métodos , Nervo Vestibulococlear/anatomia & histologia
18.
Neurosurgery ; 65(6): 1147-52; discussion 1152-3, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19934974

RESUMO

OBJECTIVE: Surgical treatment of aneurysms of the anterior communicating artery complex is challenging, owing to its intricate vascular anatomy. Endoscopy is a recently rediscovered neurosurgical technique that could lend itself well to overcoming some of the vascular visualization challenges associated with this procedure. The purpose of this study was to quantify and compare the working area afforded by the microscope and the endoscope to the anterior communicating artery complex in different surgical approaches and using image guidance. METHODS: We performed a total of 9 dissections, including mini-supraorbital, pterional, and orbitozygomatic approaches bilaterally in 5 whole, fresh cadaver heads. We used computed tomography-based image guidance for intraoperative navigation as well as for quantitative measurements. We estimated the working area of the anterior communicating artery complex region, using both a rigid endoscope (4.0 mm in diameter and 18 cm long with 0- and 30-degree lenses) and an operating microscope. Operability was qualitatively assessed by the senior authors. RESULTS: In microscopic exposure, the orbitozygomatic approach provided the greatest working area (204.5 +/- 33.9 mm2), as compared with the mini-supraorbital approach (114.8 +/- 26.9 mm2) and pterional approach (170 +/- 20.4 mm2; P < 0.05). Evaluation of the endoscopic working area showed that the supraorbital approach, using both 0- and 30-degree endoscopes, provided a working area greater than that of a conventional pterional approach (P < 0.05) and comparable to that of an orbitozygomatic approach (P > 0.05). CONCLUSION: In our model, use of the endoscope, in an assistive manner to microscopic surgery, provided a working area advantage without loss of microneurosurgical techniques of dissection or of depth perception in the surgical field. This advantage was most prominent when smaller craniotomies were used.


Assuntos
Artéria Cerebral Anterior/cirurgia , Craniotomia/métodos , Microcirurgia/métodos , Neuronavegação , Cadáver , Endoscopia/métodos , Humanos , Microscopia/métodos
19.
Neurosurgery ; 64(5 Suppl 2): 437-42; discussion 442-4, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19404122

RESUMO

OBJECTIVE: The transoral approach is the most direct and commonly used method to access the ventral craniocervical junction. Recently, an endonasal, endoscopic approach to the craniovertebral junction was proposed. We reasoned that the coupling of the endoscope with the direct transoral approach and image guidance could result in a minimally invasive, simple approach to the ventral craniovertebral junction. We investigated the potential usefulness of such an approach in a cadaver model. METHODS: A direct transoral approach to the craniovertebral junction was performed using computed tomography-based image guidance in 9 fresh adult head specimens. Endoscopic odontoidectomy was performed in 5 specimens. In the remaining 4 specimens, the surgical working area and surgical freedom associated with an endoscopic and a microscopic approach to the ventral craniovertebral junction were evaluated and compared. In these 4 specimens, we also measured and compared the exposure of the clivus provided by the endoscope and by the operating microscope without splitting the soft palate. RESULTS: With variously angled endoscopic assistance and image guidance, it was possible to tailor the excision of the anterior arch of the atlas and to precisely identify the odontoid process and its related ligaments intraoperatively, resulting in a complete and controlled odontoidectomy. The surgical area exposed over the posterior pharyngeal wall was significantly improved using the endoscope (606.5 +/- 127.4 mm3) compared with the operating microscope (425.7 +/- 100.8 mm3), without any compromise of surgical freedom (P < 0.05). The extent of the clivus exposed with the endoscope (9.5 +/- 0.7 mm) without splitting the soft palate was significantly improved compared with that associated with microscopic approach (2.0 +/- 0.4 mm) (P < 0.05). CONCLUSION: With the aid of the endoscope and image guidance, it is possible to approach the ventral craniovertebral junction transorally with minimal tissue dissection, no palatal splitting, and no compromise of surgical freedom. In addition, the use of an angled-lens endoscope can significantly improve the exposure of the clivus without splitting the soft palate. An endoscope-assisted transoral approach is a direct and powerful tool for the treatment of surgical pathology at the craniovertebral junction.


Assuntos
Articulação Atlantoaxial/cirurgia , Articulação Atlantoccipital/cirurgia , Endoscopia/métodos , Microcirurgia/métodos , Boca/cirurgia , Procedimentos Neurocirúrgicos/métodos , Articulação Atlantoaxial/anatomia & histologia , Articulação Atlantoccipital/anatomia & histologia , Cadáver , Atlas Cervical/anatomia & histologia , Atlas Cervical/cirurgia , Humanos , Ligamentos/anatomia & histologia , Ligamentos/cirurgia , Microscopia/instrumentação , Microscopia/métodos , Microcirurgia/instrumentação , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Monitorização Intraoperatória/instrumentação , Monitorização Intraoperatória/métodos , Boca/anatomia & histologia , Neuronavegação/métodos , Procedimentos Neurocirúrgicos/instrumentação , Osso Occipital/anatomia & histologia , Osso Occipital/cirurgia , Processo Odontoide/anatomia & histologia , Processo Odontoide/cirurgia , Faringe/anatomia & histologia , Faringe/cirurgia , Tomografia Computadorizada por Raios X/métodos
20.
J Med Case Rep ; 3: 53, 2009 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-19203370

RESUMO

INTRODUCTION: Intracranial arachnoid cysts are considered to be congenital malformations with a predilection for the temporal fossa. They are often asymptomatic but can sometimes be symptomatic due to enlargement or hemorrhage. There are multiple case reports of arachnoid cysts becoming symptomatic with hemorrhagic complications following head trauma. In such cases, the bleeding is often confined to the side ipsilateral to the arachnoid cyst. Occurrence of contralateral subdural hematomas in patients with temporal fossa arachnoid cysts has rarely been observed and is reported less frequently in the medical literature. CASE PRESENTATION: We report two cases of people (a 23-year-old man and a 41-year-old man) with temporal fossa arachnoid cysts complicated by a subdural hematoma following head injury. Both patients developed a subdural hematoma contralateral to the side of a temporal fossa arachnoid cyst. It is likely that lack of adequate intracranial cushioning in the presence of an intracranial arachnoid cyst may result in injury not only to ipsilateral but also to contralateral bridging veins, following head trauma. CONCLUSION: It is important to identify and report such rare complications with intracranial arachnoid cysts, so that asymptomatic patients with an intracranial arachnoid cyst can be counseled about such possibilities following head trauma.

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