Detalhe da pesquisa
1.
Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.
J Biol Chem
; 294(32): 11980-11991, 2019 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160323
2.
Moderate chronic ethanol consumption exerts beneficial effects on nonalcoholic fatty liver in mice fed a high-fat diet: possible role of higher formation of triglycerides enriched in monounsaturated fatty acids.
Eur J Nutr
; 59(4): 1619-1632, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31161349
3.
Identification of Modulators of the C. elegans Aryl Hydrocarbon Receptor and Characterization of Transcriptomic and Metabolic AhR-1 Profiles.
Antioxidants (Basel)
; 11(5)2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624894
4.
Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.
Nat Struct Mol Biol
; 12(6): 554-5, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15908963
5.
Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.
Oxid Med Cell Longev
; 2018: 4396403, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30147834
6.
Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol
; 25(6): 666-676.e4, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576532
7.
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
Endocrinology
; 144(2): 528-33, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12538613
8.
Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.
Mol Cell Endocrinol
; 217(1-2): 181-8, 2004 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-15134816
9.
Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor.
J Steroid Biochem Mol Biol
; 92(5): 469-76, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15698552
10.
Structural determinants of ligand binding to the mineralocorticoid receptor.
Mol Cell Endocrinol
; 350(2): 187-95, 2012 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21820032
11.
Structural basis of spirolactone recognition by the mineralocorticoid receptor.
Mol Pharmacol
; 72(3): 563-71, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17569793
12.
The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.
Mol Pharmacol
; 71(2): 473-82, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17105867
13.
The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor.
Mol Pharmacol
; 67(5): 1714-22, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15716462