Detalhe da pesquisa
1.
Gauging innovation and health impact from biomedical research: survey results and interviews with recipients of EU-funding in the fields of Alzheimer's disease, breast cancer and prostate cancer.
Health Res Policy Syst
; 21(1): 66, 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37386455
2.
Poor Translatability of Biomedical Research Using Animals - A Narrative Review.
Altern Lab Anim
; 51(2): 102-135, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36883244
3.
Effects of caloric restriction on immunosurveillance, microbiota and cancer cell phenotype: Possible implications for cancer treatment.
Semin Cancer Biol
; 73: 45-57, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271317
4.
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies.
Arch Toxicol
; 95(6): 1867-1897, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851225
5.
Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: A focus on human studies.
Pharmacol Res
; 152: 104579, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790820
6.
Oral microbiota and Alzheimer's disease: Do all roads lead to Rome?
Pharmacol Res
; 151: 104582, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794871
7.
Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept.
Environ Health
; 19(1): 23, 2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093744
8.
Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods.
Toxicol Appl Pharmacol
; 354: 7-18, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476865
9.
Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies.
Pharmacol Res
; 131: 32-43, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555333
10.
Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition.
Toxicol Appl Pharmacol
; 280(2): 378-88, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25150140
11.
Transitioning biomedical research toward human-centric methodologies: systems-based strategies.
Drug Discov Today
; 29(4): 103947, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460569
12.
Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems.
Stem Cell Reports
; 19(1): 37-40, 2024 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134927
13.
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Stem Cell Reports
; 19(5): 604-617, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670111
14.
Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing.
Reprod Toxicol
; 117: 108358, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863571
15.
Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro-in vivo extrapolation.
Front Pharmacol
; 14: 1136174, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959852
16.
MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?
J Neurooncol
; 106(1): 33-41, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21725802
17.
Sporadic Alzheimer's Disease- and Neurotoxicity-Related microRNAs Affecting Key Events of Tau-Driven Adverse Outcome Pathway Toward Memory Loss.
J Alzheimers Dis
; 86(3): 1427-1457, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213375
18.
In Vitro-In Vivo Extrapolation by Physiologically Based Kinetic Modeling: Experience With Three Case Studies and Lessons Learned.
Front Toxicol
; 4: 885843, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924078
19.
Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation.
Reprod Toxicol
; 110: 124-140, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378221
20.
A worldwide survey on the use of animal-derived materials and reagents in scientific experimentation.
Eng Life Sci
; 22(9): 564-583, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36093359