Detalhe da pesquisa
1.
Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers.
Blood
; 137(15): 2010-2020, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067606
2.
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.
Blood
; 135(8): 547-557, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31899794
3.
Validation of patient-reported vaso-occlusive crisis day as an endpoint in sickle cell disease studies.
Eur J Haematol
; 109(3): 226-237, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35569114
4.
Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas.
Haemophilia
; 25(5): 797-806, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31336410
5.
IL-22 induces an acute-phase response.
J Immunol
; 185(9): 5531-8, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20870942
6.
Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner.
J Immunol
; 185(7): 4213-22, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20817881
7.
Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model.
Res Pract Thromb Haemost
; 6(2): e12679, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35316941
8.
Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells.
Biochem Biophys Res Commun
; 409(3): 500-5, 2011 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21600878
9.
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Rheumatology (Oxford)
; 48(11): 1352-8, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19713442
10.
Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species.
AAPS J
; 21(3): 52, 2019 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30976993
11.
PF-04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo-Controlled Study.
Clin Transl Sci
; 12(2): 180-188, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30597771
12.
Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.
J Pharm Sci
; 107(7): 1995-2004, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29571739
13.
Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection.
Crit Care
; 11(6): R122, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18042296
14.
Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor XaI16L.
J Pharm Sci
; 106(8): 2136-2143, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28389265
15.
Different osteogenic potentials of recombinant human BMP-6 adeno-associated virus and adenovirus in two rat strains.
Tissue Eng
; 12(2): 209-19, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16548680
16.
Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors.
Int J Med Sci
; 3(3): 97-105, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16761078
17.
A gene expression profile for endochondral bone formation: oligonucleotide microarrays establish novel connections between known genes and BMP-2-induced bone formation in mouse quadriceps.
Bone
; 33(1): 46-63, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12919699
18.
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.
Int Immunopharmacol
; 4(5): 693-708, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15120653
19.
A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.
Nat Biotechnol
; 29(11): 1028-33, 2011 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22020385
20.
A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia.
Shock
; 35(5): 492-8, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21263385