Detalhe da pesquisa
1.
Targeting Plasmodium PI(4)K to eliminate malaria.
Nature
; 504(7479): 248-253, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24284631
2.
Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families.
PLoS Genet
; 9(2): e1003293, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23408914
3.
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro.
Antimicrob Agents Chemother
; 58(3): 1586-95, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366744
4.
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.
Antimicrob Agents Chemother
; 58(9): 5060-7, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913172
5.
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites.
Genome Res
; 20(11): 1534-44, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20829224
6.
The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.
PLoS Med
; 9(2): e1001169, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22363211
7.
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Proc Natl Acad Sci U S A
; 105(26): 9059-64, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18579783
8.
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.
Nat Chem Biol
; 4(6): 347-56, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18454143
9.
Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials.
Bioorg Med Chem Lett
; 20(14): 4027-31, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610151
10.
Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials.
ACS Infect Dis
; 6(4): 613-628, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32078764
11.
Cell-based optimization of novel benzamides as potential antimalarial leads.
Bioorg Med Chem Lett
; 19(24): 6970-4, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19879133
12.
Liver-Targeted Toll-Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus.
Hepatol Commun
; 3(10): 1296-1310, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31592075
13.
8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity.
ChemMedChem
; 14(4): 501-511, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30605243
14.
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum.
BMC Genomics
; 9: 513, 2008 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18973684
15.
A systematic map of genetic variation in Plasmodium falciparum.
PLoS Pathog
; 2(6): e57, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789840
16.
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
Science
; 362(6419)2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30523084
17.
Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance.
mBio
; 7(4)2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381290
18.
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.
Cell Host Microbe
; 19(1): 114-26, 2016 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26749441
19.
High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria.
ACS Infect Dis
; 2(4): 281-293, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27275010
20.
Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Cell Host Microbe
; 11(6): 654-63, 2012 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704625