Detalhe da pesquisa
1.
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
Nat Immunol
; 19(11): 1212-1223, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30323343
2.
High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
Int J Mol Sci
; 21(15)2020 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751752
3.
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases.
J Med Chem
; 67(7): 5758-5782, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511649
4.
Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis.
J Med Chem
; 65(24): 16290-16312, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36469401
5.
Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Bioorg Med Chem Lett
; 21(4): 1236-42, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21237644
6.
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Neuron
; 105(5): 837-854.e9, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31902528
7.
Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase.
Assay Drug Dev Technol
; 13(8): 466-75, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26292018