Detalhe da pesquisa
1.
Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.
Amino Acids
; 46(3): 701-15, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23881108
2.
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Cancer Cell
; 7(5): 433-44, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15894264
3.
A Pandora's box in feline medicine: presenting signs and surgical outcomes in 58 previously hoarded cats with chronic otitis media-interna.
J Feline Med Surg
; 25(9): 1098612X231197089, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37728478
4.
Generation of a novel transgenic mouse model for bioluminescent monitoring of survivin gene activity in vivo at various pathophysiological processes: survivin expression overlaps with stem cell markers.
Am J Pathol
; 176(4): 1629-38, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133811
5.
The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.
Am J Physiol Cell Physiol
; 299(1): C164-74, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20392931
6.
Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
Cancer Chemother Pharmacol
; 62(3): 517-27, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17987291
7.
Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells.
Cancer Chemother Pharmacol
; 59(6): 711-23, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17021820
8.
Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase.
Cancer Res
; 65(12): 5390-8, 2005 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15958588
9.
Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line.
Cancer Res
; 62(22): 6639-44, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12438261
10.
The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells.
Cancer Res
; 63(13): 3619-25, 2003 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12839950
11.
Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
Oncogene
; 22(32): 4964-72, 2003 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12902979
12.
Clinical efficacy, tolerability, and safety of SAM486A, a novel polyamine biosynthesis inhibitor, in patients with relapsed or refractory non-Hodgkin's lymphoma: results from a phase II multicenter study.
Clin Cancer Res
; 10(4): 1299-305, 2004 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14977828
13.
A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with Advanced solid malignancies.
Clin Cancer Res
; 8(7): 2157-66, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12114416
14.
Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
Mol Cancer Ther
; 3(7): 813-22, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15252142
15.
Synthesis and evaluation of analogues of 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine as inhibitors of tumor cell growth, trypanosomal growth, and HIV-1 infectivity.
J Med Chem
; 45(23): 5112-22, 2002 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12408722
16.
A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice.
Cancer Chemother Pharmacol
; 51(6): 488-92, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12695854
17.
Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
Cancer Chemother Pharmacol
; 67(2): 401-14, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20443003
18.
Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells.
Oncol Rep
; 24(1): 15-24, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20514439
19.
Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice.
Am J Physiol Gastrointest Liver Physiol
; 296(4): G899-909, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19164485
20.
Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences.
J Biol Chem
; 283(7): 4241-51, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18089555