Detalhe da pesquisa
1.
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.
Circ Res
; 129(3): 349-365, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34092082
2.
GS-967 and Eleclazine Block Sodium Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Mol Pharmacol
; 98(5): 540-547, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938719
3.
The sodium channel NaX : Possible player in excitation-contraction coupling.
IUBMB Life
; 72(4): 601-606, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32027092
4.
Use-Dependent Block of Human Cardiac Sodium Channels by GS967.
Mol Pharmacol
; 90(1): 52-60, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27136942
5.
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.
Stem Cells
; 32(7): 1774-88, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24648383
6.
Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias.
J Biol Chem
; 287(47): 39613-25, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23033485
7.
Epilepsy-associated SCN2A (Na V 1.2) Variants Exhibit Diverse and Complex Functional Properties.
bioRxiv
; 2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865317
8.
Epilepsy-associated SCN2A (NaV1.2) variants exhibit diverse and complex functional properties.
J Gen Physiol
; 155(10)2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37578743
9.
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
Nat Genet
; 54(3): 232-239, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210625
10.
Genomic Autopsy of Sudden Deaths in Young Individuals.
JAMA Cardiol
; 6(11): 1247-1256, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34379075
11.
Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.
Cell Stem Cell
; 27(5): 813-821.e6, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931730
12.
Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator.
J Mol Cell Cardiol
; 46(2): 257-67, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19038263
13.
The evolutionarily conserved residue A653 plays a key role in HERG channel closing.
J Physiol
; 587(Pt 11): 2555-66, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19406877
14.
The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function.
Cell Calcium
; 82: 102063, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31401388
15.
Genetic Mosaicism in Calmodulinopathy.
Circ Genom Precis Med
; 12(9): 375-385, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454269
16.
High-Throughput Functional Evaluation of KCNQ1 Decrypts Variants of Unknown Significance.
Circ Genom Precis Med
; 11(11): e002345, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30571187
17.
A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.
Structure
; 26(5): 683-694.e3, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29606593
18.
Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition.
Heart Rhythm
; 4(2): 170-4, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17275752
19.
Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.
Nat Genet
; 54(5): 735, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35474365
20.
Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenègre disease.
J Am Coll Cardiol
; 41(4): 643-52, 2003 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12598077