RESUMO
Over 19 lunar months reports of all aggressive acting-out misbehaviors as recorded by direct-care staff were evaluated and recorded on a day-by-day basis for a randomly selected sample of 20 developmentally delayed women, CA 18 to 50; MA, 9 to 18 months. All had been in continuous residence in a residential treatment center for a minimum of 31 months. A grid representing the 24-hr. period of the full moon (a), the three days prior to the day of the full moon (b), the three days after the full moon (c), and the balance of the lunar period (d) was placed over the record. Comparisons using the Duncan multiple-range test indicated that the mean number of misbehaviors on the day of the full moon was significantly higher than the mean number on any other day of the lunar period (the next highest was for the three days prior to the day of the full moon).
Assuntos
Agressão/psicologia , Astrologia , Deficiência Intelectual/psicologia , Lua , Adulto , Interpretação Estatística de Dados , Feminino , Humanos , Institucionalização , Pessoa de Meia-Idade , Fatores de TempoRESUMO
A previous report on the effect of the day of the full moon on the acting-out behavior of 20 developmentally delayed, institutionalized women showed that on the day of the full moon there were significantly more misbehaviors than on any other day during the lunar period. The records were re-evaluated to assess the frequency of acting-out behaviors on weekends and holidays as contrasted with the balance of the month. This re-evaluation indicated there was no significant difference between the weekends and holidays and the balance of the month (t = 1.14). The results were taken as support of the previous findings that on the day of the full moon there were significantly more misbehaviors than on any other day of the lunar period.
Assuntos
Encenação , Férias e Feriados , Institucionalização , Deficiência Intelectual/psicologia , Periodicidade , Viés , Ritmo Circadiano , Interpretação Estatística de Dados , Feminino , Humanos , Individualidade , LuaRESUMO
A case of a patient with tetanus is reported in whom an atracurium infusion and artificial ventilation were needed in addition to sedation to control the muscle spasms. The atracurium infusion was used for 71 days, the longest time ever recorded, at a mean rate of 1.3 mg/kg/hour at the end of infusion. The plasma atracurium and laudanosine concentrations were 1.5 micrograms/ml and 0.985 micrograms/ml respectively. Subsequently there was an exponential decline in the serum laudanosine concentration which had decreased to 0.014 micrograms/ml 24 hours later. These results suggest that prolonged use of atracurium by infusion is not associated with excessive cumulation of laudanosine when renal and hepatic function are normal.
Assuntos
Atracúrio/administração & dosagem , Tétano/terapia , Adulto , Atracúrio/farmacocinética , Humanos , Infusões Intravenosas , Isoquinolinas/sangue , Masculino , Respiração Artificial , Fatores de TempoRESUMO
A closed loop control system for vasoactive drug infusion is described using a dedicated bedside microcomputer and a single volumetric infusion pump. The signal from an indwelling arterial cannula is taken from the bedside monitor through an analogue/digital converter to a microcomputer. After signal validation changes of infusion rate are calculated and communicated to a volumetric infusion pump through an RS 232 interface. The system has been successfully employed in four patients during cardiac surgery prior to cardiopulmonary bypass and in six cardiac surgical patients in the postoperative period. In both groups mean arterial pressure was controlled within 5 mmHg of target value for 75% of infusion time, and within 10 mmHg for 90% of the duration of infusion.
Assuntos
Computadores , Infusões Parenterais , Microcomputadores , Vasodilatadores/administração & dosagem , Conversão Análogo-Digital , Humanos , Hipertensão/tratamento farmacológico , Complicações Intraoperatórias/prevenção & controle , Nitroglicerina/administração & dosagem , Nitroprussiato/administração & dosagem , Complicações Pós-Operatórias/tratamento farmacológico , Software , Vasodilatadores/uso terapêuticoRESUMO
Diaphragm pacing, which entails electrical stimulation to the phrenic nerve, is an effective means of managing patients with ventilatory insufficiency and intact lowermotor-neurone innervation of the diaphragm. The pacing apparatus is used to pace the right and left hemidiaphragms alternately to avoid fatigue, which may damage the muscle irreversibly. Among the important benefits of pacing in quadriplegics with paralysis or respiratory muscles are the social and psychological advantages of not being dependent on a mechanical ventilator.
Assuntos
Diafragma/inervação , Nervo Frênico , Insuficiência Respiratória/terapia , Adulto , Terapia por Estimulação Elétrica , Eletrodos Implantados , Humanos , Masculino , Marca-Passo ArtificialRESUMO
N-acetylcysteine (NAC) is an antioxidant agent which has been shown to benefit patients with fulminant hepatic failure. We have examined its effect in patients with chronic liver disease undergoing orthotopic liver transplantation by giving NAC during operation. In a prospective, randomized, double-blind, placebo-controlled study of 50 patients, NAC appeared to induce mild vasodilatation, improve oxygen delivery and consumption, and reduce base deficit, but data interpretation was difficult. There were no significant effects on mortality, morbidity or postoperative graft function.