Detalhe da pesquisa
1.
A novel model of nephrotic syndrome results from a point mutation in Lama5 and is modified by genetic background.
Kidney Int
; 101(3): 527-540, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34774562
2.
Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations.
PLoS Genet
; 9(1): e1003219, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382690
3.
Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing.
Mamm Genome
; 26(9-10): 486-500, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26449678
4.
Modelling age-related metabolic disorders in the mouse.
Mamm Genome
; 25(9-10): 487-96, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25118634
5.
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
PLoS Genet
; 7(10): e1002336, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22028672
6.
Modeling and Assessing Osteoarthritis in Mice by Destabilization of the Medial Meniscus (DMM).
Methods Mol Biol
; 2598: 357-373, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36355305
7.
Tissue-specific differences in the assembly of mitochondrial Complex I are revealed by a novel ENU mutation in ECSIT.
Cardiovasc Res
; 119(12): 2213-2229, 2023 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395010
8.
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
Cardiovasc Res
; 118(7): 1742-1757, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34142125
9.
The Mammalian Genome special issue on ageing.
Mamm Genome
; 27(7-8): 257-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27287757
10.
Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium.
Genetics
; 212(3): 655-665, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31126976
11.
Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background.
Sci Rep
; 9(1): 20398, 2019 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31892712
12.
Efficient clearance of opsonised apoptotic cells in the absence of PECAM-1.
Mol Immunol
; 44(6): 1135-40, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16911831
13.
Generation and Identification of Mutations Resulting in Chronic and Age-Related Phenotypes in Mice.
Curr Protoc Mouse Biol
; 8(2): e42, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29927552
14.
Studying Osteoarthritis Pathogenesis in Mice.
Curr Protoc Mouse Biol
; 8(4): e50, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30240153
15.
Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function.
Dis Model Mech
; 11(12)2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478029
16.
An N-Ethyl-N-Nitrosourea (ENU) Mutagenized Mouse Model for Autosomal Dominant Nonsyndromic Kyphoscoliosis Due to Vertebral Fusion.
JBMR Plus
; 2(3): 154-163, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283900
17.
With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions.
Mech Ageing Dev
; 160: 54-68, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27450180
18.
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.
Nat Genet
; 48(8): 912-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27376238
19.
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Nat Commun
; 7: 12444, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27534441
20.
The interrelationship between disease and ageing and the implications for longevity.
Curr Aging Sci
; 8(1): 89-94, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26054351