Detalhe da pesquisa
1.
Characterization of the Onset, Progression, and Reversibility of Morphological Changes in Mouse Lung after Pharmacological Inhibition of Leucine-Rich Kinase 2 Kinase Activity.
J Pharmacol Exp Ther
; 377(1): 11-19, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509901
2.
An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors.
Birth Defects Res B Dev Reprod Toxicol
; 107(2): 108-19, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27062127
3.
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition.
J Pharmacol Exp Ther
; 355(3): 397-409, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26407721
4.
Myocardial and reproductive system toxicity of SCH 351591, a selective phosphodiesterase-4 inhibitor, in CD-1 mice.
Toxicol Pathol
; 38(4): 568-82, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20460440
5.
Drug-induced hemolytic anemia and thrombocytopenia associated with alterations of cell membrane lipids and acanthocyte formation.
Toxicol Pathol
; 38(6): 907-22, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805317
6.
Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab.
Mol Cancer Ther
; 19(6): 1298-1307, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229606
7.
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.
J Clin Invest
; 116(5): 1310-6, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16670770
8.
GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis.
J Endocrinol
; 201(2): 219-30, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19282326
9.
Ziracin-induced congenital urogenital malformations in female rats.
Toxicol Pathol
; 33(3): 320-8, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15814361
10.
Development of hibernomas in rats dosed with phentolamine mesylate during the 24-month carcinogenicity study.
Toxicol Pathol
; 32(5): 558-66, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15603540
11.
Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation.
J Biol Chem
; 279(13): 12876-82, 2004 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-14709552