Effect of low-level laser therapy irradiation and Bio-Oss graft material on the osteogenesis process in rabbit calvarium defects: a double blind experimental study.

This study aims to assess the effect of low-level laser therapy (LLLT) irradiation and Bio-Oss graft material on the osteogenesis process in the rabbit calvarium defects. Twelve white male New Zealand rabbits were included in this study. Four 8-mm diameter identical defects were prepared on each rabbit's calvarium. One site was left as an untreated control (C), the second site was filled with Bio-Oss (B), the third site was treated with laser irradiation (L), and the fourth site treated with Bio-Oss and laser irradiation (B + L). In the laser group, a diode laser (wavelength 810 nm, output power 300 mW, irradiation mode CW, energy density 4 J/cm2) was applied immediately after surgery and then one other day for the next 20 days. After 4 and 8 weeks, the animals were sacrificed and histological and histomorphometric examinations were performed and the data were subjected to Friedman and repeated measurements ANOVA tests. Significant differences were not found regarding inflammation severity, foreign body reactions, and vitality of newly formed bone on 4th and 8th week after operation. The mean amount of new bone was 15.83 and 18.5% in the controls on the 4th and 8th week; 27.66 and 25.16% in the laser-irradiated group; 35.0 and 41.83% in Bio-Oss and 41.83 and 47.0% in the laser + Bio-Oss treated specimens with significant statistical differences (p <0.05). Application of LLLT in combination with Bio-Oss® can promote bone healing. Therefore, LLLT may be clinically beneficial in promoting bone formation in skeletal defects.

Conferred with a new life: A case report of management of a severe midface trauma and subsequent oral rehabilitation.

Maxillofacial traumas have been associated with 14%-17% of all facial injuries. The most common etiology of mid-facial traumas is motor vehicle accidents followed by interpersonal assaults. The devastating nature of maxillofacial defects makes reconstruction of the midface challenging, due to multiple required surgeries and extensive rehabilitation phase. The midface has been defined as the area between the zygomaticofrontal sutures and the maxillary occlusal plane. Midface traumas are significantly more challenging to manage compared to isolated facial since there is limited intact and unharmed framework to guide with anatomic reductions. Therefore, the appropriate surgical approach to a maxillofacial trauma must follow a systematic scheme. Besides, one of the main consequences of maxillofacial traumas is destruction of the teeth and teeth bearing alveolar bone. Oral rehabilitation utilizing dental implants of these patients must be considered to provide the higher quality of life. Here, we report the management and further oral rehabilitation of a case suffering severe midface trauma following a motor vehicle accident where the patient was hit by a lorry.