Detalhe da pesquisa
1.
Matrix-Metalloproteinase Inhibitory Study of Novel Tetrahydroisoquinoline-4-carboxylates: Design, Synthesis, and Molecular Docking Studies.
Chem Biodivers
; 20(5): e202201152, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36974341
2.
Anti-neoplastic pharmacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer.
Apoptosis
; 27(1-2): 49-69, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837562
3.
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation.
Angiogenesis
; 20(1): 55-71, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27743086
4.
Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation.
Biochem Biophys Res Commun
; 484(1): 85-92, 2017 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104392
5.
Immunomodulatory glc/man-directed Dolichos lablab lectin (DLL) evokes anti-tumour response in vivo by counteracting angiogenic gene expressions.
Clin Exp Immunol
; 189(1): 21-35, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28268243
6.
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development.
Bioorg Chem
; 71: 55-66, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28139247
7.
Synthesis and an angiolytic role of novel piperazine-benzothiazole analogues on neovascularization, a chief tumoral parameter in neoplastic development.
Bioorg Chem
; 65: 110-7, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26918263
8.
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton's lymphoma.
Bioorg Chem
; 65: 73-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26874345
9.
Synthesis of oxadiazole-morpholine derivatives and manifestation of the repressed CD31 Microvessel Density (MVD) as tumoral angiogenic parameters in Dalton's Lymphoma.
Bioorg Chem
; 60: 136-46, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26005956
10.
New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression.
Biochem Biophys Res Commun
; 448(2): 139-44, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24780400
11.
Steroidal alkaloid solanidine impedes hypoxia-driven ATM phosphorylation to switch on anti-angiogenesis in lung adenocarcinoma.
Phytomedicine
; 119: 154981, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531902
12.
A systems biology investigation of curcumin potency against TGF-ß-induced EMT signaling in lung cancer.
3 Biotech
; 12(11): 306, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36276461
13.
Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour.
Pharmacol Rep
; 74(2): 353-365, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35001321
14.
Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia.
Pharmacol Rep
; 73(5): 1344-1360, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34109572
15.
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma.
Biomed Pharmacother
; 112: 108707, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970513
16.
Purification and characterization of butyrate-induced protein phosphatase involved in apoptosis of Ehrlich ascites tumor cells.
Biochim Biophys Acta
; 1770(1): 39-47, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17029793
17.
Butyrate-induced phosphatase regulates VEGF and angiogenesis via Sp1.
Arch Biochem Biophys
; 478(1): 85-95, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18655767
18.
The tumor antagonistic steroidal alkaloid Solanidine prompts the intrinsic suicidal signal mediated DFF-40 nuclear import and nucleosomal disruption.
Life Sci
; 199: 139-150, 2018 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29524520
19.
The Novel 4-Phenyl-2-Phenoxyacetamide Thiazoles modulates the tumor hypoxia leading to the crackdown of neoangiogenesis and evoking the cell death.
Eur J Med Chem
; 143: 1826-1839, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133037
20.
Synthesis and amelioration of inflammatory paw edema by novel benzophenone appended oxadiazole derivatives by exhibiting cyclooxygenase-2 antagonist activity.
Biomed Pharmacother
; 103: 1446-1455, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29864929