RESUMO
ABSTRACT: Arsenic compounds are colorless and odorless and toxicity can occur either acutely following ingestion of arsenicals with gastrointestinal disturbances or due to chronic exposure usually presenting with dermatologic lesions and peripheral neuropathy. We report a young couple who presented with signs and symptoms of painful sensorimotor peripheral neuropathy in a typical "stocking and glove" pattern. They had raised urinary arsenic levels with normal blood levels and thus, a diagnosis of chronic arsenic poisoning due to contaminated water intake was made after detecting elevated arsenic levels in their home water supply. Both patients underwent chelation therapy with dimercaprol for 14 days and reported subjective and objective improvement in symptoms with the reduction in urinary arsenic levels at the end of therapy.
Assuntos
Intoxicação por Arsênico , Doenças do Sistema Nervoso Periférico , Humanos , Intoxicação por Arsênico/complicações , Doenças do Sistema Nervoso Periférico/induzido quimicamente , Masculino , Feminino , Adulto , Dimercaprol/uso terapêutico , Quelantes/uso terapêutico , Arsênio/urina , Resultado do Tratamento , Doença Crônica , Terapia por QuelaçãoRESUMO
Clostridium litorale is a Gram-positive, rod-shaped, and spore-forming bacterium, which is able to use amino acids such as glycine, sarcosine, proline, and betaine as single carbon and energy sources via Stickland reactions. The genome consists of a circular chromosome (3.41 Mb) and a circular plasmid (27 kb).