Detalhe da pesquisa
1.
Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells.
J Biol Chem
; 291(21): 11252-67, 2016 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27030009
2.
A novel 3D high-content assay identifies compounds that prevent fibroblast invasion into tissue surrogates.
Exp Cell Res
; 339(1): 35-43, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475730
3.
3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions.
Exp Cell Res
; 323(1): 131-143, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24480576
4.
Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling.
Cell Chem Biol
; 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38537632
5.
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis.
Mol Biol Cell
; 18(10): 4024-36, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17671160
6.
Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.
J Med Chem
; 63(15): 8025-8042, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338514
7.
Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo.
Clin Cancer Res
; 25(4): 1404-1414, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429199
8.
Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.
J Med Chem
; 62(2): 928-940, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563338
9.
High-content analysis in preclinical drug discovery.
Comb Chem High Throughput Screen
; 11(3): 216-30, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18336214
10.
Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death.
Cell Death Dis
; 8(3): e2709, 2017 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28358364
11.
Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity.
Mol Cancer Ther
; 15(4): 583-92, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26832791
12.
Quantification of histone H3 Lys27 trimethylation (H3K27me3) by high-throughput microscopy enables cellular large-scale screening for small-molecule EZH2 inhibitors.
J Biomol Screen
; 20(2): 190-201, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409661
13.
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.
Proc Natl Acad Sci U S A
; 99(18): 11808-12, 2002 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-12189207