Detalhe da pesquisa
1.
Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent ß-amyloid generation.
Cell
; 147(3): 615-28, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036569
2.
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.
Proc Natl Acad Sci U S A
; 107(37): 16325-30, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20736350
3.
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.
Proc Natl Acad Sci U S A
; 107(37): 16320-4, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660762
4.
Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system.
J Neurosci
; 31(15): 5744-54, 2011 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21490216
5.
Acute Presentation of Newly Diagnosed Multiple Sclerosis Associated With Polymerase Chain Reaction-Proven Human Herpesvirus 6 Central Nervous System Infection.
Cureus
; 14(4): e24319, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35607553
6.
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.
J Neurosci
; 28(9): 1997-2005, 2008 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18305234
7.
Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease.
J Neurosci
; 28(51): 13805-14, 2008 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19091971
8.
Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
J Neurosci
; 27(40): 10849-59, 2007 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17913918
9.
Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function.
Neurobiol Dis
; 29(3): 505-14, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18187333
10.
Genetically engineered mouse models of neurodegenerative diseases.
Nat Neurosci
; 5(7): 633-9, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12085093
11.
Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading.
Nat Neurosci
; 5(4): 301-7, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11889469
12.
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
J Neurosci
; 26(1): 41-50, 2006 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16399671
13.
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.
J Neurosci
; 26(45): 11798-806, 2006 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17093100
14.
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
J Neurosci
; 25(1): 192-8, 2005 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15634781
15.
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited.
J Neurosci
; 25(9): 2386-95, 2005 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15745965
16.
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress.
J Neurosci
; 25(33): 7567-74, 2005 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16107644
17.
BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.
J Neurosci
; 25(50): 11693-709, 2005 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16354928
18.
Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.
J Neurosci
; 23(8): 3272-7, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12716934
19.
Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.
J Neurosci
; 22(22): 9794-9, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12427835
20.
Stabilization of alpha-synuclein protein with aging and familial parkinson's disease-linked A53T mutation.
J Neurosci
; 24(33): 7400-9, 2004 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15317865