Detalhe da pesquisa
1.
Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4.
J Immunol
; 184(8): 4362-7, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20212095
2.
Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.
J Biol Chem
; 283(3): 1257-1266, 2008 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17977838
3.
Functional activity of MD-2 polymorphic variant is significantly different in soluble and TLR4-bound forms: decreased endotoxin binding by G56R MD-2 and its rescue by TLR4 ectodomain.
J Immunol
; 180(9): 6107-15, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18424732
4.
Transfer of monomeric endotoxin from MD-2 to CD14: characterization and functional consequences.
J Biol Chem
; 282(50): 36250-6, 2007 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17934216
5.
Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain.
J Biol Chem
; 282(2): 1010-7, 2007 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17121827
6.
Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase.
J Biol Chem
; 282(11): 7877-84, 2007 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17227775
7.
OmpR-dependent and OmpR-independent responses of Escherichia coli to sublethal attack by the neutrophil bactericidal/permeability increasing protein.
Mol Microbiol
; 43(6): 1493-504, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11952900