[Vitiligo Combined With Annular Lichen Planus: A Rare Case Report].

A 36-year-old female patient came to our hospital with the chief complaint of having white patches on her waist for 10-plus years and having new annular plaques appearing on the white patches for 6-plus months. Wood's lamp examination done in the hospital showed a positive result. Histopathology of skin tissue from the edge of the annular swelling on the right waist revealed epidermal hyperkeratosis, wedge-shaped thickening of the granular layer, liquefactive degeneration of the basal cells, and a band-like infiltration of lymphocytes in the superficial dermis. The patient was diagnosed with vitiligo combined with annular lichen planus (ALP). The patient was treated with topical halometasone cream administered twice a day. The purplish-red annular plagues subsided and disappeared almost completely one month after the treatment was started and no signs of recurrence were observed duringn the 2-month follow-up. ALP is a rare variant of lichen planus. There has been no reported case of vitiligo combined with ALP so far.

[Textual Research on Chiding Disease and Matixiang Herb in Da he wai ke (External Medicine of Da He)].

Recorded in Da he wai ke (The External Medicine of Da He) in the Ming dynasty without a corresponding disease title in contemporary scholarly concepts of Traditional Chinese Medicine (TCM), Chiding disease was described as an acute symptomatic disease with inevitable serious conditions of convulsion-like or mania-like behavior, and as a refractory ailment. It was also considered as an alias of Hongsiding (namely the acute lymphangitis) in few ancient books. Matixiang, a Chinese herb for treatment of Chiding, was regarded as a nonsuch drug by Da he wai ke, and was considered as a take-then-cure drug by Chuang yang jing yan quan shu (Compendium for Experience in Sores Diseases). The present studies about Chiding and Matixiang show that: (1) the name of Chiding was first seen in Zhong zang jing (Master Hua's Classic of the Viscera) ; (2) Chiding was rarely mentioned in medical literature of the Song, Yuan and Qing Dynasty, but mostly seen in the Ming Dynasty; (3) Xinding and Huoyanding were found as synonyms of Chiding ; (4) the distinction between Chiding and Hongsiding (flaming sore) was revealed by comparison analysis of their etiology, affected part(s), symptoms, prognosis and syndromic pictures; (5) Chiding on the tongue is the same as "Tongue Ding" or "Sublingual Ding" in contemporary TCM and as "Sublingual Space Infection" in Western Medicine. Moreover, Chiding on the hands, feet or other skin parts could be classified as "Hands/Feet Ding" in contemporary TCM and as "Furuncle" (i.e., Acute Suppurative Folliculitis and Perifolliculitis or cellulites of the tongue) in Western Medicine; (6) Matixiang is probably deduced as Asarum forbesii Maxim., A. ichangense C. Y. Cheng et C. S. Yang, family Aristolochiaceae, or Valeriana jatamansi Jones., family Valerianaceae.

[Study of the contents of Da He Wai Ke in the Ming Dynasty].

Da He Wai Ke (the Great River External Medicine), an ancient book written by WANG Quan, a folk doctor, who was an apprentice of an unknown mysterious person in the Ming Dynasty. There are two volumes: thirty-six diseases were recorded in volume 1 with a figure for each disease before the descriptive texts, and 72 prescriptions were recorded in volume 2. The current research results about the origin of the contents of this book showed that: (1) contents in volume 1 texts were mainly from Chuang Ke Tong Xuan Lun (Enigmatic Theories for Sores Diseases); (2) there are no any direct clues about the source of the illustrations in volume 1. Though some of them are similar to those in Chuang Yang Jing Yan Quan Shu (the Collected Works for Experience in Sores (Diseases), it is impossible that the illustrations are from that book; (3) the disease names listed in Da He Wai Ke were basically consistent with the ones in an ancient Korean book entitled 36 Zhong Tu Lu (the 36 Illustrated Abscess Diseases); (4) the clues about where 67 of 72 prescriptions in volume 2 came from were revealed; (5) it was found that 27 of 37 prescriptions in the first half of volume 2 were rewritten from Chuang Ke Tong Xuan Lun, and 24 of them were completely corresponding to the prescriptions mentioned in volume 1; (6) 35 prescriptions in the second half of volume 2, showing no correlation with volume 1, were confirmed as subsequent supplements by Wang's descendants. Of the 35 prescriptions, 12 had close relationship to those in Chuang Yang Jing Yan Quan Shu : it is assumed that authors of the two books used the same books as their reference.

[Author, date and editions of Dahe Waike in the Ming Dynasty].

Written by WANG Quan in the Ming Dynasty, Dahe Waike is a TCM surgery monograph with both figures and texts. Barely mentioned in other medical works, the edition published in the 38(th) year of the Wanli Period (1610) and held in the National Archives of Japan (No. 050-0004 I) has been taken as a unique work of great value. Other names of the book, the author's birthplace, the time of writing and the continuation of editions of the book were still unknown. Our study shows that: one of the other names of the book is Huisheng Waike Yifang, which has exactly the same content as Dahe Waike; Dahe is the abbreviation of Dahewei which was the site of the garrison troops in the Ming Dynasty and is located in Yellow River Basin (from Hexia County, Chuzhou District, Huaian City, Jiangsu Province to the Yuntiguan Site); the book was completed in the 5(th) year of the Yongle Period (1407); contents about Yangmeichuang were added in the book in later years (first recorded in the Hongzhi and Zhengde Periods); there are now 9 editions and the relationship of those editions is almost clear. Those results are of great value for research and use of the book.