[The new blood test bio-marker SEPT9 and colorectal carcinoma screening]. / Nový krevní test bio-markeru SEPT9 a screening kolorektálního karcinomu.

Due to its high incidence and mortality rates, the colorectal carcinoma represents a crucial medical issue. However, when it is detected in early stage there is high rate of successful treatment. Thats why, early stage cancer screening programmes were introduced into the clinical practice. They focus on the finding of hidden bleeding, using various laboratory techniques, sigmoidoscopy, and, primarily, colonoscopy. However, screening programmes have not yet reached the effect required. New techniques are therefore being developed, such as the detection of blood bio-markers. This group includes also methylated SEPT9 (mSEPT9) detection in blood. We applied this test on 57 patients; we divided the group into two parts. There were 33 asymptomatic individuals in the first group. In this group, we were got only one positive mSEPT9 result. The consequent colonoscopies were negative. The other group had 24 proven carcinomas. Of them, two had negative mSEPT9 results. The remaining in all 22 patients was tested mSEPT9 positive. After its efficiency is tested by further studies, this test may be used especially for patients with low compliance, as it only requires routine blood drawing.

[Endoscopic cytoscopy in examination of the digestive tract]. / Význam endoskopické cytoskopie u vysetrení trávicího traktu.

A number of new endoscopic methods have been developed recently, which aim to allow the most accurate possible viewing of the mucosa of the digestive tract. These procedures include endoscopic cytoscopy, which together with confocal endoscopy is a technique of so-called endoscopic microscopy. By means of enodcytoscopy it is possible to view "in vivo" the morphological details of the surface of the mucosa of the digestive tract. The mucosa must, however, be thoroughly cleaned and stained with methylene blue. The paper presents our own initial experience of this method, which may lead to faster and more accurate diagnosis of pre-tumorous or tumourous inflammation processes in the mucosa of the digestive tract.

[Complications of laparoscopic procedures of inguinal hernias, diagnosed on colonoscopy]. / Komplikace laparoskopické operace tríselné kýly diagnostikované kolonoskopicky.

AIM OF THE STUDY: The aim was to assess significance of colonoscopy in detection of inguinal hernias - dislocation of the mesh into the lumen of the large intestine, following inguinal hernia laparoscopic procedures (TAPP). MATERIAL, METHODOLOGY AND RESULTS: From 01-01-2004 to 31-12-2006, the authors performed 3 colonoscopies in 3 subjects after TAPP inguinal hernia laparoscopic procedures. The subjects included 2 males and 1 female, 4 to 9 months after the laparoscopic procedure, colonoscopy was performed, which was indicated for the lower abdominal pain and enterorrhagia. However, no signs of a relapsing hernia were recorded. Endoscopy detected irritation and bleeding of the sigmoid, and a mesh, which passed through the intestinal wall was detec ted in the sigmoid lumen. The subjects were then reoperated and the mesh was removed. In one subject, resection of the sigmoid had to be performed as well. The subject recovered. CONCLUSION: The postoperative complications of the TAPP procedure included dislocation of the mesh into the intestinal lumen. Detection of the mesh dislocation into the lumen of the large intestine facilitates indication for surgical management.