Detalhe da pesquisa
1.
Structure-guided optimization of small molecule c-Abl activators.
J Comput Aided Mol Des
; 28(2): 75-87, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24573412
2.
Application of Solvent-Assisted Dual-Network Hydrogel in Water-Based Drilling Fluid for Lost Circulation Treatment in Fractured Formation.
ACS Omega
; 9(1): 1166-1173, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38222518
3.
Comparative analysis of the antibacterial activity of a novel peptide deformylase inhibitor, GSK1322322.
Antimicrob Agents Chemother
; 57(5): 2333-42, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23478958
4.
Multiple Hydrogen Bonding-Assisted High-Strength Hydrogel of Silica/Polyacrylamide Nanocomposite Cross-Linked with Polyethylenimine.
ACS Omega
; 8(42): 39401-39407, 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37901508
5.
Pharmacokinetics and Safety Study of HN0037, a Novel Anti-Human Herpes Simplex Virus Inhibitor, in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 11(12): 1467-1473, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794079
6.
Discovery of Orally Bioavailable Ligand Efficient Quinazolindiones as Potent and Selective Tankyrases Inhibitors.
ACS Med Chem Lett
; 12(6): 1005-1010, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141085
7.
Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.
J Med Chem
; 62(4): 2154-2171, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30689376
8.
Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS.
ACS Med Chem Lett
; 9(7): 623-628, 2018 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30034590
9.
The Total Synthesis of Heliquinomycinone This work was supported by the National Institutes of Health (Grant numbers: AI 16943 and HL25848). The authors thank Dr. Makoto Chino of Nippon Kayaku Co., Ltd. for kindly providing a sample of heliquinomycin, and Yashuiro Itagaki of Columbia University for high-resolution mass spectral analyses.
Angew Chem Int Ed Engl
; 40(24): 4713-4716, 2001 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12404392
10.
Studies in the Total Synthesis of Heliquinomycinone: Proof of Concept and Assembly of a Fully Mature Spirocyclization Precursor This work was supported by the National Institutes of Health (Grant numbers: AI 16943 and HL25848). A Postdoctoral Fellowship is gratefully acknowledged by R.X.R. (NIH, Grant Number IF32EY06750-0181). The authors thank Dr. Daniel Chen for important initial experiments, Dr. Brian Bridgewater and Prof. Ged Parkin of Columbia University for X-ray crystal structure analysis of 11 a, and Yashuiro Itagaki for high-resolution mass spectral analyses.
Angew Chem Int Ed Engl
; 40(24): 4709-4713, 2001 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12404391
11.
Interactions of very long-chain saturated fatty acids with serum albumin.
J Lipid Res
; 43(7): 1000-10, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12091483