Detalhe da pesquisa
1.
Targeting ferroptosis in gastric cancer: Strategies and opportunities.
Immunol Rev
; 321(1): 228-245, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37903748
2.
Radioiodine-refractory differentiated thyroid cancer: Molecular mechanisms and therapeutic strategies for radioiodine resistance.
Drug Resist Updat
; 72: 101013, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38041877
3.
Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer.
Pharmacol Res
; 189: 106703, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36804016
4.
Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4.
Bioorg Med Chem
; 90: 117352, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257255
5.
Targeting KRAS mutant cancers: from druggable therapy to drug resistance.
Mol Cancer
; 21(1): 159, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35922812
6.
Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis.
Mol Cancer
; 21(1): 70, 2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35272681
7.
Inhibiting STAT3 signaling pathway by natural products for cancer prevention and therapy: In vitro and in vivo activity and mechanisms of action.
Pharmacol Res
; 182: 106357, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35868477
8.
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation.
Bioorg Med Chem
; 71: 116941, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944386
9.
Characterization of a bioactive meroterpenoid isolated from the marine-derived fungus Talaromyces sp.
Appl Microbiol Biotechnol
; 106(8): 2927-2935, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416486
10.
Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3).
J Enzyme Inhib Med Chem
; 37(1): 2004-2016, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35844184
11.
p-MEK expression predicts prognosis of patients with adenocarcinoma of esophagogastric junction (AEG) and plays a role in anti-AEG efficacy of Huaier.
Pharmacol Res
; 165: 105411, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33401002
12.
Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update.
Drug Resist Updat
; 49: 100681, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014648
13.
Targeting MDM2 for novel molecular therapy: Beyond oncology.
Med Res Rev
; 40(3): 856-880, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31587329
14.
Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance.
Mol Cancer
; 19(1): 96, 2020 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32460771
15.
Cytotoxic Nitrogenated Azaphilones from the Deep-Sea-Derived Fungus Chaetomium globosum MP4-S01-7.
J Nat Prod
; 83(4): 1157-1166, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193933
16.
Aspeterreurone A, a Cytotoxic Dihydrobenzofuran-Phenyl Acrylate Hybrid from the Deep-Sea-Derived Fungus Aspergillus terreus CC-S06-18.
J Nat Prod
; 83(6): 1998-2003, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32489099
17.
Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review.
Cell Commun Signal
; 17(1): 121, 2019 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511020
18.
Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms.
Carcinogenesis
; 39(8): 1026-1036, 2018 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29762656
19.
Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications.
Med Res Rev
; 35(6): 1220-67, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26227500
20.
NFAT as cancer target: mission possible?
Biochim Biophys Acta
; 1846(2): 297-311, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25072963