Detalhe da pesquisa
1.
Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets.
Antimicrob Agents Chemother
; 68(3): e0121023, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319076
2.
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages.
Antimicrob Agents Chemother
; 66(12): e0103222, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346232
3.
Targeting Kaposi's Sarcoma-Associated Herpesvirus ORF21 Tyrosine Kinase and Viral Lytic Reactivation by Tyrosine Kinase Inhibitors Approved for Clinical Use.
J Virol
; 94(5)2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31826996
4.
Kaposi's sarcoma-associated herpesvirus vIRF2 protein utilizes an IFN-dependent pathway to regulate viral early gene expression.
PLoS Pathog
; 15(5): e1007743, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31059555
5.
Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication.
J Virol
; 92(17)2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29950425
6.
The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
PLoS Pathog
; 13(9): e1006639, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938025
7.
Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency.
PLoS Pathog
; 13(4): e1006335, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28430817
8.
Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells.
PLoS Pathog
; 11(8): e1005105, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26295810
9.
A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.
PLoS Pathog
; 9(10): e1003640, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24146614
10.
The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells.
PLoS Pathog
; 9(11): e1003737, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24244164
11.
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Nat Commun
; 15(1): 1173, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332002
12.
Thioxothiazolo[3,4-a]quinazoline derivatives inhibit the human cytomegalovirus alkaline nuclease.
Antiviral Res
; 217: 105696, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37541625
13.
Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region.
J Virol
; 85(9): 4612-7, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307197
14.
An endothelial cell line infected by Kaposi's sarcoma-associated herpes virus (KSHV) allows the investigation of Kaposi's sarcoma and the validation of novel viral inhibitors in vitro and in vivo.
J Mol Med (Berl)
; 97(3): 311-324, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30610257