Detalhe da pesquisa
1.
Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-ß burden in several amyloid transgenic mouse models.
Glia
; 66(3): 492-504, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29134678
2.
Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.
J Neurosci
; 25(3): 629-36, 2005 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15659599
3.
A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-ß 1-42 peptide in human plasma with utility for studies of Alzheimer's disease therapeutics.
Alzheimers Res Ther
; 8(1): 58, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27978855
4.
ß-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aß5-X peptides through alternative amyloid precursor protein cleavage.
Alzheimers Res Ther
; 6(5-8): 75, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25404952
5.
Validation of assays for measurement of amyloid-ß peptides in cerebrospinal fluid and plasma specimens from patients with Alzheimer's disease treated with solanezumab.
J Alzheimers Dis
; 34(4): 897-910, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23302661
6.
A plaque-specific antibody clears existing ß-amyloid plaques in Alzheimer's disease mice.
Neuron
; 76(5): 908-20, 2012 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217740
7.
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
J Lipid Res
; 49(6): 1254-67, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18314463
8.
Activation of caspase-3 alone is insufficient for apoptotic morphological changes in human neuroblastoma cells.
J Neurochem
; 80(6): 1039-48, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11953454