Detalhe da pesquisa
1.
Novel Bacterial Topoisomerase Inhibitor Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats.
Antimicrob Agents Chemother
; 66(11): e0048322, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36255258
2.
Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies.
Toxicol Pathol
; 50(8): 930-941, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36377245
3.
International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog.
Toxicol Pathol
; 49(1): 5-109, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33393871
4.
A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia.
Cancer
; 126(6): 1264-1273, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860140
5.
Scientific Regulatory Policy Committee Points to Consider*: Nuisance Factors, Block Effects, and Batch Effects in Nonclinical Safety Assessment Studies.
Toxicol Pathol
; 48(4): 537-548, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32122253
6.
Opinion on Current Use of Non-Blinded Versus Blinded Histopathologic Evaluation in Animal Toxicity Studies.
Toxicol Pathol
; 48(4): 549-559, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32347786
7.
Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance-conferring FLT3/tyrosine kinase domain/F691 mutation.
Cancer
; 124(2): 306-314, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28960265
8.
A GNPTAB nonsense variant is associated with feline mucolipidosis II (I-cell disease).
BMC Vet Res
; 14(1): 416, 2018 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30591066
9.
Development of dietary soluble fibres by enzymatic synthesis and assessment of their digestibility in in vitro, animal and randomised clinical trial models.
Int J Food Sci Nutr
; 68(7): 849-864, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276900
10.
An Integrated Multi-Omics Analysis Defines Key Pathway Alterations in a Diet-Induced Obesity Mouse Model.
Metabolites
; 10(3)2020 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32106514
11.
Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial.
Lancet Haematol
; 7(2): e122-e133, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31837959
12.
Nutrient composition and safety evaluation of simulated isobutanol distillers dried grains with solubles and associated fermentation metabolites when fed to male Ross 708 broiler chickens (Gallus domesticus).
PLoS One
; 14(7): e0219016, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31283767
13.
Safety evaluation of HOWARU® Restore (Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium animalis subsp. lactis Bl-04 and B. lactis Bi-07) for antibiotic resistance, genomic risk factors, and acute toxicity.
Food Chem Toxicol
; 110: 316-324, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29080807
14.
Safety evaluation of AB-LIFE(®) (Lactobacillus plantarum CECT 7527, 7528 and 7529): Antibiotic resistance and 90-day repeated-dose study in rats.
Food Chem Toxicol
; 92: 117-28, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27016492
15.
Oral repeated-dose systemic and reproductive toxicity of 6:2 fluorotelomer alcohol in mice.
Toxicol Rep
; 2: 130-143, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-28962345
16.
Pathway-based toxicity: history, current approaches and liver fibrosis and steatosis as prototypes.
ALTEX
; 31(4): 407-21, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24954301
17.
Pathology review of proliferative lesions of the exocrine pancreas in two chronic feeding studies in rats with ammonium perfluorooctanoate.
Toxicol Rep
; 1: 85-91, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-28962229
18.
Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid.
Toxicology
; 326: 62-73, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25456267
19.
Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action.
ALTEX
; 31(4): 500-19, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24535319