RESUMO
Teenagers are valuable resources in communities and they are faced with multiple risk factors. Factors such as family attachment, devotion to family, parent's educational level, and parental support are the protective factors against high-risk behaviors. The purpose of this study was to determine the prevalence of drug use among pre-university students and its relationship with familial factors. 1000 Fourth grade high-school male students were randomly selected during 6 months in four districts of Shiraz City during 2017-2018. 14% of the participants were current smokers, 13.5% had a history of alcohol consumption, and 1% used psychotropic drugs, respectively. Moreover 59% of the participants who had consumed alcohol were cigarette smokers as well. 4.5% of them used all the three substances such as alcohol, tobacco and psychotropic drugs. Children whose parents do not set clear regulations or do not control their children are at higher risk of drug abuse.