Detalhe da pesquisa
1.
Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics.
J Chem Inf Model
; 62(10): 2571-2585, 2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467856
2.
The Identification of a SIRT6 Activator from Brown Algae Fucus distichus.
Mar Drugs
; 15(6)2017 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28635654
3.
N-Acylethanolamines Bind to SIRT6.
Chembiochem
; 17(1): 77-81, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607666
4.
Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis.
Drug Metab Dispos
; 43(12): 1891-904, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26400396
5.
In silico prediction of the site of oxidation by cytochrome P450 3A4 that leads to the formation of the toxic metabolites of pyrrolizidine alkaloids.
Chem Res Toxicol
; 28(4): 702-10, 2015 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25651456
6.
Identification of a new reactive metabolite of pyrrolizidine alkaloid retrorsine: (3H-pyrrolizin-7-yl)methanol.
Chem Res Toxicol
; 27(11): 1950-7, 2014 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25295702
7.
Rational design of novel CYP2A6 inhibitors.
Bioorg Med Chem
; 22(23): 6655-6664, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25458499
8.
SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors.
Pharmaceuticals (Basel)
; 16(1)2023 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36678624
9.
CYP2A6: genetics, structure, regulation, and function.
Drug Metabol Drug Interact
; 27(2): 73-88, 2012 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22706231
10.
Profiling the regulatory interplay of BET bromodomains and Sirtuins in cancer cell lines.
Biomed Pharmacother
; 147: 112652, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35065514
11.
Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells.
Biomed Pharmacother
; 138: 111452, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33684691
12.
Impact of structurally diverse BET inhibitors on SIRT1.
Gene
; 741: 144558, 2020 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32165310
13.
Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities.
Biomed Pharmacother
; 131: 110701, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32905943
14.
Quercetin based derivatives as sirtuin inhibitors.
Biomed Pharmacother
; 111: 1326-1333, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30841446
15.
Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle.
Sci Rep
; 9(1): 19672, 2019 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31873175
16.
Natural polyphenols as sirtuin 6 modulators.
Sci Rep
; 8(1): 4163, 2018 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29515203
17.
Sirtuin 6 (SIRT6) Activity Assays.
Methods Mol Biol
; 1436: 259-69, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27246220
18.
Common and Distinct Interactions of Chemical Inhibitors with Cytochrome P450 CYP1A2, CYP2A6 and CYP2B6 Enzymes.
Drug Metab Lett
; 10(1): 56-64, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26648056
19.
Studying SIRT6 regulation using H3K56 based substrate and small molecules.
Eur J Pharm Sci
; 63: 71-6, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25004411
20.
Quantitative insights for the design of substrate-based SIRT1 inhibitors.
Eur J Pharm Sci
; 59: 12-9, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747578