RESUMO
THE AIM OF REVIEW: To verify the role of nutrition in development of Nonalcoholic Fatty Liver Disease in patients with metabolic syndrome. ORIGINAL POSITIONS: The article contains main conceptions of etiology and pathogenesis of Nonalcoholic Fatty Liver Disease. Spesial attention gives to the role of nutrition in development of this case. The are own dates presented, which shows relationship between degree of obesity, factual nutrition and expression of morphological changes in liver in patients with Nonalcoholic Fatty Liver Disease. CONCLUSION: Nutrition mistakes in patients with Nonalcoholic Fatty Liver Disease are: excess of energy, animal proteins and fats, deficit of nutrition fibres, carbohydrates, antioxidants, vitamins B1, B2, PP. The main directions of diet in patients with Nonalcoholic Fatty Liver Disease.
Assuntos
Fígado Gorduroso/dietoterapia , Fígado Gorduroso/etiologia , Estado Nutricional , Obesidade/complicações , Índice de Massa Corporal , Humanos , Hepatopatia Gordurosa não Alcoólica , Necessidades Nutricionais , Obesidade/dietoterapia , Estresse OxidativoRESUMO
A survey of existing methods of pathogenetic and symptomatic treatment of primary biliary cirrhosis has been made and it has reviewed prospective directions of its therapy. Is also presents a retrospective analysis of our own data of S-adenosylmethionine (Heptral) in 27 patients PBC receiving UDCA basic therapy. In its application intravenously of 400 mg 2 times daily for 3 weeks showed a reduction in the severity of pruritus, assessed by visual analogue scale, a subjective decrease fatigability and a decrease level of serum bilirubin.
Assuntos
Cirrose Hepática Biliar/tratamento farmacológico , Anticorpos Monoclonais/administração & dosagem , Anticorpos Monoclonais/uso terapêutico , Fadiga/tratamento farmacológico , Fadiga/etiologia , Glucocorticoides/administração & dosagem , Glucocorticoides/uso terapêutico , Humanos , Imunossupressores/administração & dosagem , Imunossupressores/uso terapêutico , Cirrose Hepática Biliar/complicações , Guias de Prática Clínica como Assunto , Prurido/tratamento farmacológico , Prurido/etiologia , Receptores Citoplasmáticos e Nucleares/agonistas , S-Adenosilmetionina/administração & dosagem , S-Adenosilmetionina/uso terapêutico , Resultado do Tratamento , Ácido Ursodesoxicólico/administração & dosagem , Ácido Ursodesoxicólico/uso terapêuticoRESUMO
The article is devoted to the problems of the well-timed diagnosis of autoimmune liver diseases, such as autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis and overlap-syndromes. It has been shown that diagnosis verification influences on the course of these conditions and the patient's longevity. The causes of last diagnosis and clinical and laboratory data have been analyzed. The authors based on literature facts, obtained results and their experience have advised the number of recommendations to improve the diagnosis of autoimmune liver disease. The well-timed diagnosis permits to elevate the longevity and to advance the quality of life.