Multi-U-Net: Residual Module under Multisensory Field and Attention Mechanism Based Optimized U-Net for VHR Image Semantic Segmentation.

As the acquisition of very high resolution (VHR) images becomes easier, the complex characteristics of VHR images pose new challenges to traditional machine learning semantic segmentation methods. As an excellent convolutional neural network (CNN) structure, U-Net does not require manual intervention, and its high-precision features are widely used in image interpretation. However, as an end-to-end fully convolutional network, U-Net has not explored enough information from the full scale, and there is still room for improvement. In this study, we constructed an effective network module: residual module under a multisensory field (RMMF) to extract multiscale features of target and an attention mechanism to optimize feature information. RMMF uses parallel convolutional layers to learn features of different scales in the network and adds shortcut connections between stacked layers to construct residual blocks, combining low-level detailed information with high-level semantic information. RMMF is universal and extensible. The convolutional layer in the U-Net network is replaced with RMMF to improve the network structure. Additionally, the multiscale convolutional network was tested using RMMF on the Gaofen-2 data set and Potsdam data sets. Experiments show that compared to other technologies, this method has better performance in airborne and spaceborne images.

A systematic review of the efficacy of donepezil hydrochloride combined with nimodipine on treating vascular dementia.

BACKGROUND: Vascular dementia (VaD) is a comprehensive syndrome related to the damage of cognitive function and various cerebral vascular illnesses. VaD is also generally recognized as the second most common type of dementia after Alzheimer disease, contributing to 30% of the dementia population in Asia and developing countries. The ability of donepezil hydrochloride and nimodipine had been respectively proven in improving cognitive function in vascular dementia. However, whether the combined application of both drugs contribute to better efficacy remains as a research hotspot. Studies had shown definite satisfactory result with such combination, however evidence-based evaluation of the efficacy is still lacking. Therefore, meta-analysis is employed in this study to evaluate the efficacy and safety of using donepezil hydrochloride combined with nimodipine in treating VaD to provide references for clinical treatments. The efficacy of donepezil hydrochloride combined with nimodipine on treating vascular dementia is systematically reviewed to provide evidence-based references for clinical applications. METHODS: Both Chinese and English databases were searched from the start till August, 2020 for any RCT regarding the combined use of the 2 drugs in treating vascular dementia. Two investigators would later evaluate and screened out research and data based on an improved Jaded scale. Software Rev Man 5.3.0 was employed to carry out meta-analysis on clinical effificacy, mini-mental state examination (MMSE) ratings, activity of daily living (ADL) ratings, and clinical dementia scale (CDR) ratings. RESULTS: Donepezil hydrochloride combined with nimodipine had demonstrated satisfactory efficacy on the treatment of vascular dementia. Improvements were namely spotted on MMSE scale, ADL scale, and CDR scale, with the utmost efficacy by 12 weeks after intervention. CONCLUSIONS: Donepezil hydrochloride combined with nimodipine had good efficacy in the treatment of patients with vascular dementia, mainly in terms of improving the Simple MMSE scores, the ability to use daily living scale (ADL) scores and the CDR, and the best results were obtained after 12 weeks of intervention. Such conclusion should be cautiously evaluated.

Characteristics of aerosol optical depth over land types in central Asia.

Aerosols are an important contributor to global atmospheric changes and have critical effects on the climate system. Regionally, aerosols in central Asia comprise a significant portion of global aerosols. Based on aerosol optical depth (AOD)Level 2 daily product data and land cover type product data, the long-term AOD characteristics of six major land use/cover types and their relationships with landscape metrics are discussed. Contribution analysis is applied to quantitatively estimate the effects of land use/cover on regional AOD over central Asia. The results show that series of daily AODs over six land uses/covers display remarkable annual cyclic variations and obvious seasonal changes. The annual average AODs for barren land and cropland are highest, followed by regional AODs. There are different frequencies and times of occurrence for high AOD values of various land types. Urban areas are one of the major contributors to the regional atmosphere in winter; grasslands have a great influence on regional AOD decreases. Barren land always has a high contribution to the regional AOD. The land use types affected by anthropogenic activities were smaller contributors to regional aerosols than barren lands affected by climate factors. This paper advances the understanding of relationship between aerosols and land use/cover and facilitates land use decision making.

A new species of the genus Leptobrachella Smith, 1925 (Anura, Megophryidae) from Guizhou, China.

Asian leaf-litter toads of the genus Leptobrachella represent charismatic anuran diversification with 80 species, of which 25 are from China. Recent new discoveries suggest that the diversity of this genus is underestimated. Here, we describe a new species of Leptobrachella, Leptobrachella bashaensis sp. nov. from the Basha Nature Reserve, Congjiang County, Guizhou Province, China. The new species is distinguished from its congeners by the following suite of morphological traits: small body size (SVL 22.9-25.6 mm in six adult males and 27.1 mm in one adult female); head longer than wide; dorsal skin slightly shagreened with small tubercles; creamy-white chest and belly with irregular black spots; distinct ventrolateral glands forming a white line; finger webbing and fringes absent; toe webbing rudimentary and lateral fringes narrow; iris bicolored with bright orange in upper half and silver in lower half; dorsal surface of tadpole head dark brown with small, brown, irregular spot, air sac-shaped bulges on both sides of body. The new species differs from all known congeners by an uncorrected p-distance of >5.3% of the 16S rRNA gene fragment examined, and the phylogenetic analysis clusters the new species with L. maoershanensis and L. laui. At present, the new species is only known from a small range of montane evergreen secondary forests in Basha Nature Reserve approximately 900 m elevation. Its natural history and conservation status are discussed.