Detalhe da pesquisa
1.
Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability.
Cell
; 163(6): 1388-99, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26627736
2.
Non-genetic and genetic rewiring underlie adaptation to hypomorphic alleles of an essential gene.
EMBO J
; 40(21): e107839, 2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34528284
3.
Epistasis, aneuploidy, and functional mutations underlie evolution of resistance to induced microtubule depolymerization.
EMBO J
; 40(22): e108225, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605051
4.
Emerging and evolving concepts in gene essentiality.
Nat Rev Genet
; 19(1): 34-49, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033457
5.
H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase.
Drug Resist Updat
; 71: 100993, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639774
6.
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33653953
7.
Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor.
Cell
; 135(5): 879-93, 2008 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19041751
8.
One rogue agent suffices for genomic chaos.
Nature
; 566(7743): 188-189, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737500
9.
Characterization of a panARS-based episomal vector in the methylotrophic yeast Pichia pastoris for recombinant protein production and synthetic biology applications.
Microb Cell Fact
; 15(1): 139, 2016 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27515025
10.
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast.
Nature
; 468(7321): 321-5, 2010 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20962780
11.
Karyotypic changes as drivers and catalyzers of cellular evolvability: a perspective from non-pathogenic yeasts.
Semin Cell Dev Biol
; 24(4): 332-8, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403271
12.
Karyotypic determinants of chromosome instability in aneuploid budding yeast.
PLoS Genet
; 8(5): e1002719, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22615582
13.
Whole-Genome Duplication Shapes the Aneuploidy Landscape of Human Cancers.
Cancer Res
; 82(9): 1736-1752, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35502547
14.
Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae.
J Cell Biol
; 174(1): 39-51, 2006 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16818718
15.
Polarized cell growth: double grip by CDK1.
Curr Biol
; 17(15): R600-3, 2007 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17686432
16.
P53 induces senescence in the unstable progeny of aneuploid cells.
Cell Cycle
; 19(24): 3508-3520, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305692
17.
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis.
Oncogene
; 39(44): 6816-6840, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32978522
18.
The conditional nature of gene essentiality.
Curr Opin Genet Dev
; 58-59: 55-61, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31470233
19.
The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology.
Front Genet
; 10: 713, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31447882
20.
Environmental stresses induce karyotypic instability in colorectal cancer cells.
Mol Biol Cell
; 30(1): 42-55, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30379607