RESUMO
Three chromosomal rearrangements: a balanced reciprocal translocation, t(14;10) (q22;q13), a Y-autosome translocation, t(Y;16) (q11;p13) and a deleted Y chromosome, Yq- were detected among 100 infertile men. The autosomal translocation, associated with oligozoospermia was found to be familial with various effects on the female carriers and the proband's father. The patients with the chromosome Y abberations were found to be azoospermic and might have lost the genes necessary for normal spermatogenesis.
Assuntos
Aberrações Cromossômicas , Oligospermia/genética , Adulto , Deleção Cromossômica , Cromossomos Humanos 13-15 , Cromossomos Humanos 16-18 , Cromossomos Humanos 6-12 e X , Feminino , Humanos , Masculino , Linhagem , Espermatogênese , Translocação Genética , Cromossomo YRESUMO
AIDS developed in a blood donor-recipient pair in Israel. Transmission of HTLV III/LAV probably occurred via a blood transfusion in November 1979. The donor was asymptomatic at the time of blood donation, but initial symptoms of AIDS-related complex developed in the donor 3 months later and in the recipient 6 months following the blood transfusion.