Detalhe da pesquisa
1.
Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell
; 186(5): 987-998.e15, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36764290
2.
NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.
Cell
; 184(26): 6299-6312.e22, 2021 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861190
3.
Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins.
Cell
; 179(2): 485-497.e18, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31543266
4.
Antibodies expand the scope of angiotensin receptor pharmacology.
Nat Chem Biol
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744986
5.
Structure of a nascent membrane protein as it folds on the BAM complex.
Nature
; 583(7816): 473-478, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32528179
6.
Rational design of proteasome inhibitors based on the structure of the endogenous inhibitor PI31/Fub1.
Proc Natl Acad Sci U S A
; 120(51): e2308417120, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091293
7.
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
Nat Chem Biol
; 19(8): 1013-1021, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37081311
8.
Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Nature
; 575(7783): 545-550, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31581174
9.
Chaperone-mediated assembly of the proteasome core particle - recent developments and structural insights.
J Cell Sci
; 135(8)2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451017
10.
Mechanism of proteasome gate modulation by assembly chaperones Pba1 and Pba2.
J Biol Chem
; 298(5): 101906, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35398095
11.
Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM.
Proc Natl Acad Sci U S A
; 115(8): 1795-1800, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29434040
12.
Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure.
Biochim Biophys Acta Biomembr
; 1860(2): 378-383, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993151
13.
The changing landscape of membrane protein structural biology through developments in electron microscopy.
Mol Membr Biol
; 33(1-2): 12-22, 2016 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27608730
14.
The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy.
Biochim Biophys Acta
; 1848(2): 496-501, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450810
15.
Rotating with the brakes on and other unresolved features of the vacuolar ATPase.
Biochem Soc Trans
; 44(3): 851-5, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27284051
16.
PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanism.
J Biol Chem
; 289(23): 16399-408, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24795045
17.
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
Bioorg Med Chem Lett
; 24(3): 911-6, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398298
18.
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
bioRxiv
; 2024 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328185
19.
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat Struct Mol Biol
; 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600324
20.
Mechanism of autocatalytic activation during proteasome assembly.
Nat Struct Mol Biol
; 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600323