Detalhe da pesquisa
1.
Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation.
Clin Infect Dis
; 67(4): 504-512, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617982
2.
Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria gonorrhoeae.
Antimicrob Agents Chemother
; 62(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249694
3.
Lifitegrast for the Treatment of Dry Eye Disease: Results of a Phase III, Randomized, Double-Masked, Placebo-Controlled Trial (OPUS-3).
Ophthalmology
; 124(1): 53-60, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28079022
4.
Lifitegrast Ophthalmic Solution 5.0% versus Placebo for Treatment of Dry Eye Disease: Results of the Randomized Phase III OPUS-2 Study.
Ophthalmology
; 122(12): 2423-31, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365210
5.
Safety and pharmacokinetics of lisdexamfetamine dimesylate in adults with clinically stable schizophrenia: a randomized, double-blind, placebo-controlled trial of ascending multiple doses.
J Clin Psychopharmacol
; 34(6): 682-9, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25310201
6.
Self-Reported quality of life in adults with attention-deficit/hyperactivity disorder and executive function impairment treated with lisdexamfetamine dimesylate: a randomized, double-blind, multicenter, placebo-controlled, parallel-group study.
BMC Psychiatry
; 13: 253, 2013 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24106804
7.
Design of Two Phase III, Randomized, Multicenter Studies Comparing Gepotidacin with Nitrofurantoin for the Treatment of Uncomplicated Urinary Tract Infection in Female Participants.
Infect Dis Ther
; 11(6): 2297-2310, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271314
8.
Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague.
Sci Transl Med
; 14(647): eabg1787, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35648812
9.
Systematic review and meta-analysis to estimate the antibacterial treatment effect of nitrofurantoin for a non-inferiority trial in uncomplicated urinary tract infection.
J Glob Antimicrob Resist
; 22: 68-77, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32084607
10.
Pharmacokinetics of Gepotidacin in Renal Impairment.
Clin Pharmacol Drug Dev
; 9(5): 560-572, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32429000
11.
Safety and tolerability of lifitegrast ophthalmic solution 5.0%: Pooled analysis of five randomized controlled trials in dry eye disease.
Eur J Ophthalmol
; 29(4): 394-401, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30112930
12.
Pharmacokinetics, Safety, and Tolerability Evaluation of Single and Multiple Doses of GSK3342830 in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 8(6): 754-764, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536589
13.
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study.
Lancet Neurol
; 7(9): 796-804, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18703004
14.
Ocular comfort assessment of lifitegrast ophthalmic solution 5.0% in OPUS-3, a Phase III randomized controlled trial.
Clin Ophthalmol
; 12: 263-270, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440868
15.
A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis.
Curr Med Res Opin
; 22(9): 1671-8, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16968570
16.
Lifitegrast clinical efficacy for treatment of signs and symptoms of dry eye disease across three randomized controlled trials.
Curr Med Res Opin
; 32(10): 1759-1765, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27388660
17.
Safety of Lifitegrast Ophthalmic Solution 5.0% in Patients With Dry Eye Disease: A 1-Year, Multicenter, Randomized, Placebo-Controlled Study.
Cornea
; 35(6): 741-8, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055211
18.
Lisdexamfetamine dimesylate in adults with attention-deficit/ hyperactivity disorder who report clinically significant impairment in executive function: results from a randomized, double-blind, placebo-controlled study.
J Clin Psychiatry
; 74(7): 694-702, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23945447
19.
A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis.
Arthritis Rheum
; 56(9): 3096-106, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17763439