RESUMO
Postmenopausal period disturbances are more frequently observed in women with unhealthy lifestyles, insufficient physical activity is related to increased cardiovascular risk (CVR). There is a lack of evidence-based information on physical activity in postmenopausal women and its relationship with CVR factors, including D vitamin serum levels. OBJECTIVE: To determine the physical activity level in postmenopausal women from the Colombia Caribbean and establish relationships between the physical activity and biochemical and anthropometric CVR factors. METHODS: A correlational descriptive study in which 183 postmenopausal women were linked for convenience sampling. Level of physical activity (International Physical Activity Questionnaire) and their relationships with anthropometric variables, blood pressure, lipid profile, glycemic and serum vitamin D were evaluated. RESULTS: According to the physical activity, 82.5% of women were classified as inactive, 9.3% as insufficiently active and only 8.2% as physically active. Physical inactivity was significantly related to higher glucose, triglycerides, and total cholesterol serum levels (Pâ<â.05). The prevalence of the women with vitamin D levels less than 30âng/mL were of 69.9%. The women physically active and with eutrophic nutritional condition had more high levels of vitamin D. CONCLUSIONS: 82.5% of the postmenopausal women evaluated were physically inactive and this condition was associated with higher serum levels of glycemic, total cholesterol and triglycerides. Serum vitamin D concentrations were higher in traffic and physically active women.
RESUMO
BACKGROUND: Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome. OBJECTIVE: To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women. METHODS: This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean. The serum 25-OH-D levels and the anthropometric and biochemical markers were assessed and correlated with metabolic syndrome. RESULTS: The average value of serum vitamin D (25-OH-D) was 26.34 ± 9.08 ng/mL, and 69.95% of the women had vitamin D levels <30 ng/mL, of which 43.72% were with insufficiency (<30 to >20 ng/mL) and 26.23% with deficiency (<20 ng/mL). Of the evaluated women, the 81.42% seemed to have metabolic syndrome. Through the linear regression, one significant positive association was observed between the HDL cholesterol and the 25-OH-D levels (P=0.014). CONCLUSION: In the evaluated population in this study, vitamin D deficiency is related with low HDL cholesterol levels.
RESUMO
Resumen Objetivo: determinar los valores séricos de la enzima lecitina colesterol aciltransferasa en un grupo de mujeres postmenopáusicas, y establecer su relación con factores asociados a riesgo cardiovascular. Materiales y métodos: estudio descriptivo transversal prospectivo, correlacional, que incluyó 56 mujeres postmenopáusicas en quienes se evaluaron variables antropométricas y bioquímicas (perfil lipídico y glicemia basal) asociadas a riesgo cardiovascular y se correlacionaron con las concentraciones séricas de lecitina colesterol aciltransferasa. Resultados: los valores séricos promedio de dicha enzima fueron 7,89 ± 1,26 (g/ml. Las mujeres con valores de índice de masa corporal superior a 25 tienen niveles séricos de lecitina colesterol aciltransferasa significativamente mayores que aquellas que tienen índice de masa corporal normal. No se observaron relaciones significativas entre los niveles de lecitina colesterol aciltransferasa y las variables bioquímicas evaluadas. Conclusiones: este trabajo es uno de los primeros que evalúa los niveles séricos de lecitina colesterol aciltransferasa en mujeres postmenopáusicas del Caribe colombiano. Se encontró una relación significativa entre los niveles séricos de lecitina colesterol aciltransferasa y los valores de índice de masa corporal elevados. Se requieren nuevos estudios para entender mejor la relación entre los niveles séricos de lecitina colesterol aciltransferasa y el riesgo cardiovascular en mujeres postmenopáusicas.
Abstract Objective: To determine the serum levels of lecithin cholesterol acyltransferase in a group of postmenopausal women and to establish their relationship with factors associated with cardiovascular risk. Materials and methods: A descriptive, correlational and cross-sectional study was performed that included 56 postmenopausal women. Anthropometric and biochemical (lipid profile and baseline blood glucose) variables associated with cardiovascular risk were measured, and were correlated with the serum concentrations of lecithin cholesterol acyltransferase. Results: The mean serum level of lecithin cholesterol acyltransferase was 7.89 ± 1.26 (g/ml. The women with a body mass index greater than 25 had significantly higher serum levels of the enzyme than those that had a normal body mass index. No significant relationships were observed between the levels of lecithin cholesterol acyltransferase and the biochemical variables evaluated. Conclusions: This study is one of the first that has evaluated the serum levels of lecithin cholesterol acyltransferase in postmenopausal women of the Colombian Caribbean. A significant relationship was found between the serum levels of lecithin cholesterol acyltransferase and elevated values of the body mass index. Further studies are required for a better understanding of the relationship between the serum levels of lecithin cholesterol acyltransferase and cardiovascular risk in postmenopausal women.