Detalhe da pesquisa
1.
Adaptive sequence divergence forged new neurodevelopmental enhancers in humans.
Cell
; 185(24): 4587-4603.e23, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423581
2.
Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.
Cell
; 166(5): 1269-1281.e19, 2016 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27565349
3.
From Prescription to Transcription: Genome Sequence as Drug Target.
Cell
; 162(1): 16-7, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26140587
4.
Multicenter integrated analysis of noncoding CRISPRi screens.
Nat Methods
; 21(4): 723-734, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38504114
5.
Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13.
Proc Natl Acad Sci U S A
; 120(38): e2221448120, 2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695916
6.
Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data.
Genome Res
; 32(6): 1183-1198, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35609992
7.
Targeted long-read sequencing identifies missing disease-causing variation.
Am J Hum Genet
; 108(8): 1436-1449, 2021 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34216551
8.
AP-1 subunits converge promiscuously at enhancers to potentiate transcription.
Genome Res
; 31(4): 538-550, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674350
9.
Correcting signal biases and detecting regulatory elements in STARR-seq data.
Genome Res
; 31(5): 877-889, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33722938
10.
Transgenic mice for in vivo epigenome editing with CRISPR-based systems.
Nat Methods
; 18(8): 965-974, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34341582
11.
Causal network inference from gene transcriptional time-series response to glucocorticoids.
PLoS Comput Biol
; 17(1): e1008223, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513136
12.
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.
Genome Res
; 28(9): 1272-1284, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30097539
13.
Bayesian estimation of genetic regulatory effects in high-throughput reporter assays.
Bioinformatics
; 36(2): 331-338, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31368479
14.
Distinct properties of cell-type-specific and shared transcription factor binding sites.
Mol Cell
; 52(1): 25-36, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076218
15.
Predicting gene structure changes resulting from genetic variants via exon definition features.
Bioinformatics
; 34(21): 3616-3623, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29701825
16.
Clustering gene expression time series data using an infinite Gaussian process mixture model.
PLoS Comput Biol
; 14(1): e1005896, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337990
17.
Genomic approaches for understanding the genetics of complex disease.
Genome Res
; 25(10): 1432-41, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26430153
18.
Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort.
Genome Res
; 25(8): 1206-14, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26084464
19.
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.
Genome Res
; 25(8): 1158-69, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26025803
20.
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
Nat Methods
; 12(12): 1143-9, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26501517