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Nat Biotechnol ; 28(9): 935-42, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20829833

RESUMO

Biological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery.


Assuntos
Biologia Computacional/métodos , Biologia Computacional/normas , Disseminação de Informação , Redes e Vias Metabólicas , Transdução de Sinais , Software , Bases de Dados como Assunto , Linguagens de Programação
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