Detalhe da pesquisa
1.
Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids.
Nucleic Acids Res
; 50(14): e79, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524555
2.
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Antimicrob Agents Chemother
; 66(1): e0153521, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606338
3.
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
PLoS Pathog
; 16(11): e1008932, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33141865
4.
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3.
Proc Natl Acad Sci U S A
; 115(38): 9616-9621, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185555
5.
Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei.
PLoS Pathog
; 13(3): e1006279, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334017
6.
Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.
Nucleic Acids Res
; 45(15): 9030-9045, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28911117
7.
NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.
Nucleic Acids Res
; 43(9): 4491-504, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25873624
8.
CRISPR/Cas9-based precision tagging of essential genes in bloodstream form African trypanosomes.
Mol Biochem Parasitol
; 249: 111476, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378143
9.
Mechanistic insight into the catalytic activity of ßßα-metallonucleases from computer simulations: Vibrio vulnificus periplasmic nuclease as a test case.
Chembiochem
; 12(17): 2615-22, 2011 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22114054
10.
Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus.
Mol Biochem Parasitol
; 163(1): 28-38, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18940204
11.
Edelfosine induces an apoptotic process in Leishmania infantum that is regulated by the ectopic expression of Bcl-XL and Hrk.
Antimicrob Agents Chemother
; 52(10): 3779-82, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18644968
12.
Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes.
Sci Rep
; 8(1): 7960, 2018 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29785042
13.
Impulsiveness and Child-to-Parent Violence: The Role of Aggressor's Sex.
Span J Psychol
; 20: E15, 2017 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219469
14.
ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.
PLoS One
; 10(6): e0130365, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26090847
15.
Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.
PLoS One
; 9(2): e89526, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24651293
16.
Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.
Front Cell Infect Microbiol
; 3: 78, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24294594
17.
5'-Trityl-substituted thymidine derivatives as a novel class of antileishmanial agents: Leishmania infantum EndoG as a potential target.
ChemMedChem
; 8(7): 1161-74, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23625887
18.
Autophagy in trypanosomatids.
Cells
; 1(3): 346-71, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24710480