Associations of ureteroceles location and system anatomy with outcomes of endoscopic treatment: A systematic review and meta-analysis.

INTRODUCTION: Ureteroceles are a congenital abnormality of the ureter that can cause significant complications. Endoscopic treatment is a commonly used treatment approach. The aim of this review is to assess the results of endoscopic treatment for ureteroceles with consideration to their location and system anatomy. METHODS: A meta-analysis was conducted by searching electronic databases for studies comparing outcomes of endoscopic treatment for ureteroceles. Newcastle-Ottawa Scale (NOS) was employed to evaluate the potential for bias. The primary outcome was the rate of secondary procedures required following endoscopic treatment. Secondary outcomes were inadequate drainage and post-operative vesicoureteral reflux (VUR) rates. A subgroup analysis was performed to investigate possible causes of heterogeneity in the primary outcome. The statistical analysis was conducted using Review Manager 5.4. RESULTS: There were 28 retrospective observational studies, published between 1993 and 2022, including 1044 patients with primary outcomes in this meta-analysis. The quantitative synthesis showed that ectopic and duplex system ureteroceles were significantly associated with higher rate of secondary operation compared to intravesical and single system ureteroceles, respectively (OR: 5.42, 95% CI: 3.93-7.47; and OR: 5.10, 95% CI: 3.31-7.87). The associations were still significant in subgroup analysis based on follow up duration, average age at surgery, and duplex system only. For secondary outcomes, incidence of inadequate drainage were significantly higher in ectopic (OR: 2,01, 95% CI: 1.18-3.43), but not in duplex system ureteroceles (OR: 1.94, 95% CI: 0,97-3.86). Post-operative VUR rates were higher in both ectopic (OR: 1.79, 95% CI: 1.29-2.47) and duplex system ureteroceles group (OR: 1.88, 95% CI: 1.15-3.08). CONCLUSION: Ectopic ureteroceles and duplex system ureteroceles were associated with worse outcomes following endoscopic treatment compared to intravesical and single system ureteroceles, respectively. It is recommended to carefully select patients, conduct pre-operative evaluations, and closely monitor patients with ectopic and duplex system ureteroceles.

The learning curve for a single surgeon using ultrasonography to guide supine percutaneous nephrolithotomy with an alken metal telescopic dilator.

Ultrasound (US) has three advantages over fluoroscopy for guiding percutaneous nephrolithotomy (PNCL): it provides an assessment of adjacent structures and real-time puncture adjustment, and is radiation free. This study aimed to define the number of procedures that should be performed to achieve competence in US-guided PCNL using an Alken metal telescopic dilator. A non-randomised retrospective study with consecutive sampling was used for the study design. A total of 50 patients above 18 years of age with the largest diameter of renal stone ≥20 mm were included. They were divided into five groups based on timing of the surgery to evaluate and visualise improvements based on primary outcomes within the groups. Line charts were used, and statistical analysis was performed to evaluate the learning curve. Most of the base characteristics between the groups were similar. Tract dilatation time decreased significantly after 20 PCNLs were performed (p < 0.001). Stone-free status markedly increased after 20 PCNLs were performed (p < 0.001). Postoperative fever (10%) and need for blood transfusion (26%) were the only complications. Basic competency was achievable after 20 PCNL procedures were performed, and further improvements in outcomes were achieved after 40 PCNLs with an acceptable rate of non-severe complications.

Minimally invasive transurethral laser incision for management of ectopic ureter orifice stenosis in adult patient.

The aim of this report is to present our experience of performing transurethral laser incision for management of ectopic ureter orifice stenosis in adult patient. A 61-year-old male was presented with right flank pain. Computed tomography urography showed right complete double collecting system, upper moiety hydroureteronephrosis, and parenchymal thinning of the upper moiety. Cystoscopy showed right ectopic ureter orifice on the prostatic part of the urethra. Transurethral laser incision was performed at the 12 o'clock position of the stenotic orifice with Thulium laser. This report showed that transurethral laser incision was a minimally invasive procedure with good result.