Detalhe da pesquisa
1.
A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer.
Cancer Immunol Immunother
; 72(3): 759-767, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35976415
2.
"If only I had", patients' experiences during early oncology trials.
Support Care Cancer
; 31(5): 290, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084141
3.
Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing.
Br J Cancer
; 127(4): 776-783, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35606463
4.
First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours.
Br J Cancer
; 126(7): 1010-1017, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903842
5.
A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours.
Br J Cancer
; 124(2): 391-398, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020594
6.
Quantification and clinical validation of the selective MET kinase inhibitor DO-2 and its metabolites DO-5 and M3 in human plasma.
J Pharm Biomed Anal
; 240: 115962, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38211518
7.
Treatment Patterns and Use of Immune Checkpoint Inhibitors Among Patients with Metastatic Bladder Cancer in a Dutch Nationwide Cohort.
Eur Urol Open Sci
; 59: 50-54, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38213646
8.
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors.
Clin Cancer Res
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630781
9.
Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGFß) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors.
Clin Transl Sci
; 17(2): e13736, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38362837
10.
Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer.
Nat Commun
; 15(1): 1349, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38355607
11.
Immunotherapy in Urothelial Cancer: Stop When Achieving a Response, Restart upon Disease Progression.
Cancers (Basel)
; 15(14)2023 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37509315
12.
International consensus on the initial diagnostic workup of cancer of unknown primary.
Crit Rev Oncol Hematol
; 181: 103868, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435296
13.
Bexmarilimab-induced macrophage activation leads to treatment benefit in solid tumors: The phase I/II first-in-human MATINS trial.
Cell Rep Med
; 4(12): 101307, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38056464
14.
Genome-wide aneuploidy detected by mFast-SeqS in circulating cell-free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer.
Mol Oncol
; 16(10): 2086-2097, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35181986
15.
Anti-PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8+ T cells.
Clin Cancer Res
; 28(1): 215-226, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34615720
16.
Pain Progression at Initiation of Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC): A Post Hoc Analysis of the PROSELICA Study.
Cancers (Basel)
; 13(6)2021 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805793
17.
ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration-resistant prostate cancer patients: A phase Ib study.
Cancer Rep (Hoboken)
; 4(4): e1367, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33709626
18.
Systemic Blockade of Clever-1 Elicits Lymphocyte Activation Alongside Checkpoint Molecule Downregulation in Patients with Solid Tumors: Results from a Phase I/II Clinical Trial.
Clin Cancer Res
; 27(15): 4205-4220, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34078651
19.
Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types.
Clin Cancer Res
; 27(22): 6106-6114, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475104
20.
Impact of progression at baseline and on-treatment progression events in three large prostate cancer trials.
Eur J Cancer
; 125: 142-152, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31837907