Detalhe da pesquisa
1.
Fibroblast growth factor-induced lens fiber cell elongation is driven by the stepwise activity of Rho and Rac.
Development
; 151(3)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240393
2.
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology.
Development
; 151(1)2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38180241
3.
Lens fiber cell differentiation occurs independently of fibroblast growth factor receptor signaling in the absence of Pten.
Dev Biol
; 467(1-2): 1-13, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32858001
4.
A missense allele of PEX5 is responsible for the defective import of PTS2 cargo proteins into peroxisomes.
Hum Genet
; 140(4): 649-666, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33389129
5.
Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens.
Hum Genomics
; 13(1): 10, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770771
6.
High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses.
Hum Genet
; 138(11-12): 1391-1407, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691004
7.
N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.
Dev Biol
; 428(1): 118-134, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28552735
8.
FGFR and PTEN signaling interact during lens development to regulate cell survival.
Dev Biol
; 410(2): 150-163, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26764128
9.
Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.
Development
; 141(17): 3388-98, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25139855
10.
Frs2α enhances fibroblast growth factor-mediated survival and differentiation in lens development.
Development
; 139(24): 4601-12, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23136392
11.
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Nature
; 461(7267): 1084-91, 2009 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19847259
12.
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Nature
; 462(7275): 930-4, 2009 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016602
13.
AP-2α is required after lens vesicle formation to maintain lens integrity.
Dev Dyn
; 243(10): 1298-309, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24753151
14.
Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation.
J Biol Chem
; 288(16): 11436-47, 2013 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479732
15.
Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing.
Mol Vis
; 20: 1491-517, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25489224
16.
Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.
Exp Eye Res
; 121: 130-42, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24472646
17.
miR-26 Deficiency Causes Alterations in Lens Transcriptome and Results in Adult-Onset Cataract.
Invest Ophthalmol Vis Sci
; 65(4): 42, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38683565
18.
miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract.
bioRxiv
; 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352453
19.
3-Dimensional morphometric analysis of murine bladder development and dysmorphogenesis.
Dev Dyn
; 241(3): 522-33, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22275180
20.
Lens-specific ßA3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization.
PLoS One
; 18(3): e0281386, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36989286