RESUMO
We report 4 cases of rhinosporidiosis in the province of Cáceres. Two had nasal localization and in two ocular conjunctiva was involved. Three patients, two of which came from the same village, had the antecedent of bathing in the same stagnant water. The diagnosis was made by the microscopic observation of characteristic sporangia of Rhinosporidium seeberi in the histopathological study. The lesions did not respond to antibiotic and antiinflammatory treatment. After excision there were no recurrences, and the patients are asymptomatic after 1 1/2 year follow up.
Assuntos
Doenças da Túnica Conjuntiva/patologia , Infecções Oculares/patologia , Mucosa Nasal , Rinosporidiose/patologia , Adulto , Criança , Doenças da Túnica Conjuntiva/microbiologia , Infecções Oculares/microbiologia , Feminino , Humanos , Masculino , Doenças Nasofaríngeas/microbiologia , Doenças Nasofaríngeas/patologiaRESUMO
The clinical and morphological features of two patients with solitary extramedullary plasmacytomas of paranasal sinus and nasal cavity are presented. Patients only developed local symptomatology without features of multiple myeloma. They were treated with surgical excision and local radiotherapy. This is the treatment of choice recommended for these localized tumors. Microscopically, one tumor contained a well-differentiated plasma cell population, and the other was made up immature cells. Cytoplasmic staining for IgG was showed in both tumors for immunoperoxidase studies. However, no serum monoclone was detected at the time of diagnosis nor later. Currently, they are alive without evidence of disease 20 and 16 months, respectively, after treatment.
Assuntos
Neoplasias do Seio Maxilar , Neoplasias Nasais , Plasmocitoma , Idoso , Terapia Combinada , Feminino , Humanos , Imuno-Histoquímica , Masculino , Neoplasias do Seio Maxilar/patologia , Neoplasias do Seio Maxilar/terapia , Neoplasias Nasais/patologia , Neoplasias Nasais/terapia , Plasmocitoma/patologia , Plasmocitoma/terapiaRESUMO
The clinical, morphological, microscopic, immunohistochemical, and ultrastructural findings in a case of primary non-Hodgkin's malignant lymphoma of the prostate gland is reported. The presenting features were not distinct from those of nodular hyperplasia. Following biopsy, the lesion was classified as monoclonal IgM-secreting, low grade, malignant beta-lymphoma. We discuss the good outcome of this case and the prognostic value of several clinical and morphological parameters. Finally, the therapeutic possibilities for this tumor type are compared with those of extranodal lymphomas in other sites.