Detalhe da pesquisa
1.
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Nat Immunol
; 16(11): 1153-61, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437244
2.
A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease.
Blood
; 141(11): 1277-1292, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044666
3.
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.
Nature
; 567(7746): 43-48, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760930
4.
Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
Proc Natl Acad Sci U S A
; 118(41)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34611019
5.
IFNÉ£ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity.
Diabetologia
; 66(11): 2075-2086, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37581620
6.
Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells.
Diabetologia
; 66(5): 884-896, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36884057
7.
Thrombospondin-1, CD47, and SIRPα display cell-specific molecular signatures in human islets and pancreata.
Am J Physiol Endocrinol Metab
; 324(4): E347-E357, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791324
8.
Congenital beta cell defects are not associated with markers of islet autoimmunity, even in the context of high genetic risk for type 1 diabetes.
Diabetologia
; 65(7): 1179-1184, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501400
9.
GPA33 is expressed on multiple human blood cell types and distinguishes CD4+ central memory T cells with and without effector function.
Eur J Immunol
; 51(6): 1377-1389, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33728639
10.
Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas.
Am J Pathol
; 191(3): 454-462, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33307036
11.
A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes.
Diabetologia
; 64(2): 313-324, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33145642
12.
1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications.
Cytotherapy
; 23(3): 242-255, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33461863
13.
Clinical and genetic correlates of islet-autoimmune signatures in juvenile-onset type 1 diabetes.
Diabetologia
; 63(2): 351-361, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754749
14.
GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells.
Diabetologia
; 63(6): 1186-1198, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32248243
15.
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial.
Diabetologia
; 63(3): 597-610, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915895
16.
Multidimensional analyses of proinsulin peptide-specific regulatory T cells induced by tolerogenic dendritic cells.
J Autoimmun
; 107: 102361, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31776056
17.
Type 1 diabetes induction in humanized mice.
Proc Natl Acad Sci U S A
; 114(41): 10954-10959, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874533
18.
Abnormal islet sphingolipid metabolism in type 1 diabetes.
Diabetologia
; 61(7): 1650-1661, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29671030
19.
SLC30A8 polymorphism and BMI complement HLA-A*24 as risk factors for poor graft function in islet allograft recipients.
Diabetologia
; 61(7): 1623-1632, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29679103
20.
Islet stress, degradation and autoimmunity.
Diabetes Obes Metab
; 20 Suppl 2: 88-94, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30230178