Detalhe da pesquisa
1.
Design, Synthesis and Biological Activities of (Thio)Urea Benzothiazole Derivatives.
Int J Mol Sci
; 24(11)2023 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298442
2.
Synthesis, In Silico, and Biological Evaluation of a Borinic Tryptophan-Derivative That Induces Melatonin-like Amelioration of Cognitive Deficit in Male Rat.
Int J Mol Sci
; 23(6)2022 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35328650
3.
13C-NMR Chemical Shifts in 1,3-Benzazoles as a Tautomeric Ratio Criterion.
Molecules
; 27(19)2022 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234805
4.
Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore.
Bioorg Med Chem
; 28(9): 115427, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205045
5.
Design, synthesis, molecular docking and in vitro evaluation of benzothiazole derivatives as 11ß-hydroxysteroid dehydrogenase type 1 inhibitors.
Mol Divers
; 24(4): 1-14, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31664610
6.
Aromatic Regions Govern the Recognition of NADPH Oxidase Inhibitors as Diapocynin and its Analogues.
Arch Pharm (Weinheim)
; 350(10)2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28833480
7.
Synthetic Procedures to Access 2-Guanidinobenzazoles of Biological Interest.
Curr Org Synth
; 20(5): 504-522, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35708075
8.
N-substitution Reactions of 2-Aminobenzimidazoles to Access Pharmacophores.
Curr Org Synth
; 20(2): 177-219, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35272598
9.
LC-MS metabolomic evidence metabolites from Oenothera rosea L´ Hér. ex Ait with antiproliferative properties on DU145 human prostate cancer cell line.
Biomed Pharmacother
; 165: 115193, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517287
10.
Decrease in Cell Viability of Breast Cancer Cells by a Di-Hydroxylated Derivative of N-(2-hydroxyphenyl)-2-Propylpentanamide.
Anticancer Agents Med Chem
; 22(9): 1802-1812, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34525926
11.
Identification and evaluation of boronic compounds ameliorating cognitive deficit in orchiectomized rats.
J Trace Elem Med Biol
; 72: 126979, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35364473
12.
Dihydropyrazole-Carbohydrazide Derivatives with Dual Activity as Antioxidant and Anti-Proliferative Drugs on Breast Cancer Targeting the HDAC6.
Pharmaceuticals (Basel)
; 15(6)2022 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745608
13.
Estrous cycle phase affects myocardial infarction through reactive oxygen species and nitric oxide.
Front Biosci (Landmark Ed)
; 26(12): 1434-1443, 2021 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34994158
14.
Monoamines and their Derivatives on GPCRs: Potential Therapy for Alzheimer's Disease.
Curr Alzheimer Res
; 16(10): 871-894, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30963972
15.
Oenothera rosea L´Hér. ex Ait attenuates acute colonic inflammation in TNBS-induced colitis model in rats: in vivo and in silico myeloperoxidase role.
Biomed Pharmacother
; 108: 852-864, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30372897
16.
Current Tools and Methods in Molecular Dynamics (MD) Simulations for Drug Design.
Curr Med Chem
; 23(34): 3909-3924, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27237821
17.
Asp32 and Asp228 determine the selective inhibition of BACE1 as shown by docking and molecular dynamics simulations.
Eur J Med Chem
; 124: 1142-1154, 2016 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27639619
18.
Virtual and In Vitro Screens Reveal a Potential Pharmacophore that Avoids the Fibrillization of Aß1-42.
PLoS One
; 10(7): e0130263, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26172152
19.
π-stacking and C-X...D (X = H, NO2; D = O, π) interactions in the crystal network of both C-H...N and π-stacked dimers of 1,2-bis(4-bromophenyl)-1H-benzimidazole and 2-(4-bromophenyl)-1-(4-nitrophenyl)-1H-benzimidazole.
Acta Crystallogr C Struct Chem
; 70(Pt 1): 55-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24399227
20.
In silico and in vitro studies to elucidate the role of Cu2+ and galanthamine as the limiting step in the amyloid beta (1-42) fibrillation process.
Protein Sci
; 22(10): 1320-35, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23904252