RESUMO
BACKGROUND: The aim of this study was to assess long-term quality of life (QoL) over a period of 6 years in women with breast cancer (BC) who underwent sentinel lymph node biopsy (SLNB), axillary lymph node dissection (ALND), or SLNB followed by ALND. METHODS: The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ)-C30 and the EORTC-QLQ-BR-23 questionnaires were used to assess QoL before surgery, just after surgery, 6, 12 and 72 months later. The longitudinal effect of surgical modalities on QoL was assessed with a mixed model analysis of variance for repeated measurements. RESULTS: Five hundred and eighteen BC patients were initially included. The median follow-up was 6 years. During the follow-up, 61 patients died. None of the patients of the SLNB group developed lymphedema during follow-up and the relapse rate was similar in the different groups (P=0.62). Before surgery, global health status (P=0.52) and arm symptoms (BRAS) (P=0.99) QoL scores were similar whatever the surgical procedure. The BRAS score (P=0.0001) was better in the SLNB group 72 months after surgery. Moreover, during follow-up, patients treated with SLNB had lower arm symptoms scores than ALND patients and there was no difference for arm symptoms between patients treated with ALND and those treated with SLNB followed by complementary ALND. CONCLUSION: Long-term follow-up showed that SLNB was associated with less morbidity than ALND.
Assuntos
Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Biópsia de Linfonodo Sentinela , Idoso , Imagem Corporal/psicologia , Neoplasias da Mama/psicologia , Neoplasias da Mama/cirurgia , Carcinoma Ductal de Mama/psicologia , Carcinoma Ductal de Mama/cirurgia , Feminino , Seguimentos , Nível de Saúde , Humanos , Excisão de Linfonodo/efeitos adversos , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/cirurgia , Qualidade de Vida , Biópsia de Linfonodo Sentinela/efeitos adversos , Biópsia de Linfonodo Sentinela/psicologia , Inquéritos e Questionários , Fatores de TempoRESUMO
BACKGROUND: This prospective multicenter study assessed and compared the impact of different surgical procedures on quality of life (QoL) in breast cancer patients. PATIENTS AND METHODS: The EORTC QLQ-C30 and the EORTC QLQ-BR-23 questionnaires were used to assess global health status (GHS), arm (BRAS) and breast (BRBS) symptom scales, before surgery, just after surgery and 6 and 12 months later. The Kruskal-Wallis test with the Bonferroni correction was used to compare scores. A mixed model analysis of variance for repeated measurements was then applied to assess the longitudinal effect of surgical modalities on QoL. RESULTS: Before surgery, GHS (P = 0.7807) and BRAS (P = 0.7688) QoL scores were similar whatever the surgical procedure: sentinel node biopsy (SLNB), axillary node dissection (ALND) or SLNB + ALND. As compared with other surgical groups, GHS 75.91 [standard deviation (SD) = 17.44, P = 0.041] and BRAS 11.39 (SD = 15.36, P < 0.0001) were better in the SLNB group 12 months after surgery. Whatever the type of surgery, GHS decreased after surgery (P < 0.0001), but increased 6 months later (P = 0.0016). BRAS symptoms increased just after surgery (P = 0.0329) and until 6 months (P < 0.0001) before decreasing (P < 0.0001). CONCLUSIONS: SLNB improved GHS and BRAS QoL in breast cancer patients. However, surgeons must be cautious, SLNB with ALND results in a poorer QoL.
Assuntos
Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Linfonodos/patologia , Linfonodos/cirurgia , Estudos de Coortes , Feminino , Humanos , Excisão de Linfonodo , Metástase Linfática , Pessoa de Meia-Idade , Estudos Prospectivos , Qualidade de Vida , Biópsia de Linfonodo SentinelaRESUMO
The authors report a case of a pancreatic pseudocyst complicated by a false aneurysm of the superior mesenteric artery. The diagnosis was made possible thanks to the evocative images of echography and C.T. scanning permitting to perform on time the arteriography. The surgical treatment consisted on the exclusion of the false aneurysm, which necessitated a distal bypass to revascularise the intestinal tract, and the drainage of the pseudocyst by a Roux-en-Y loop. A review of literature is made.
Assuntos
Aneurisma/complicações , Artérias Mesentéricas , Cisto Pancreático/complicações , Pseudocisto Pancreático/complicações , Adulto , Aneurisma/diagnóstico , Aneurisma/cirurgia , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Pseudocisto Pancreático/cirurgiaAssuntos
Fístula Intestinal/complicações , Perfuração Intestinal/complicações , Cistos Ovarianos/complicações , Doenças do Colo Sigmoide/complicações , Divertículo do Colo/complicações , Feminino , Humanos , Fístula Intestinal/cirurgia , Perfuração Intestinal/cirurgia , Cistos Ovarianos/cirurgia , Doenças do Colo Sigmoide/cirurgiaRESUMO
We report the case of a liver abscess resulting from the intra hepatic migration of a toothpick coming from the stomach.